and hispidin from Peganum harmala and Inonotus hispidus with binding affinity to Candida rugosa lipase: In silico and in vitro studies.
Peganumharmala is a rich source of simple [beta]-carboline alkaloids such as harmine, harmaline
, tetrhydroharmine, harmol, harmalol, Harman [1-3].
The vine is rich in [beta]-carboline alkaloids such as harmine, tetrahydroharmine (THH), and harmaline
, and P.
The four secondary metabolites were vasicine, vasicinone, harmine, and harmaline
. These twenty-three compounds were identified in the methanol extracts of P.
The beta-carboline alkaloids harmine, tetrahydroharmine, and harmaline
found in the vines of B.
The main toxins are the alkaloids whose chemical structure is associated with an indole nucleus with a pyridinol: harmane, harmine, harmaline
, and harmalol (= harmol) .
Banisteriopsis caapi contains the alkaloids harmine, harmaline
and tetrahydroharmine, all of which belong to the [beta]-carboline group of compounds.
Ayahuasca is a vegetable beverage cooked on fire, a lightly dense liquid for oral administration that is native to the Amazon forest; it contains, at least, two kinds of plants: the Banisteriopsis caapi vine (a source of harmine and harmaline
, with a monoamine oxidase inhibiting action -IMAO) and the Psychotria viridis bush (rich in DMT).
The early phase of CF development is also influenced by the patterns of olivary activity, as shown by persistence of multiple CFs in PCs until at least 3 months of age following administration of harmaline
, which abnormally synchronizes olivary neuron activity .
Previous in vitro studies showed that the crude extracts of APP, containing VAS, DVAS, harmine and harmaline
, may have effective anti-asthmatic activities (Amin and Mehta, 1959; Hider et al., 1981 ; Nie et al., 2004).
Of chief importance is the pan Amazonian hallucinogenic brew Ayahuasca, which is a preparation containing Beta carboline alkaloids (viz.Harmine, Harmaline
and tetrahydroharmine, which act as MAOIs) contained in the vine Banisteriopsis caapi , which is boiled with the leafs of DMT containing plants, commonly used are Psychotria viridis, P.
caapi contains 13-carbolines such as harmine, harmaline
, and tetrahydroharmine in the stem.