heavy chain


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Related to heavy chain: light chain, heavy chain disease

heavy chain

n.
Either of the two larger polypeptide chains in an immunoglobulin molecule, consisting of a variable region that contains the antigen-binding portion and a constant region that is specific to each immunoglobulin class or subclass.

heavy chain

n
(Medicine) immunol a type of polypeptide chain present in an immunoglobulin molecule
References in classic literature ?
The dog rushed forth from a niche in the wall, shaking his heavy chain, and sniffing all round Cornelius in order so much the better to recognise him in case he should be ordered to pounce upon him.
At the head of the table sat Prior Vincent of Emmet all clad in soft robes of fine cloth and silk; on his head was a black velvet cap picked out with gold, and around his neck hung a heavy chain of gold, with a great locket pendant therefrom.
They were succeeded by a clanking noise, deep down below; as if some person were dragging a heavy chain over the casks in the wine merchant's cellar.
I know how listlessly and wearily each of that wretched pair dragged on their heavy chain through a world that was poisoned to them both.
to be peeped at like a wild lion through the iron bars--to gnash one's teeth and howl, through the long still night, to the merry ring of a heavy chain and to roll and twine among the straw, transported with such brave music.
When she paid the coachman she took her money out of a hard steel purse, and she kept the purse in a very jail of a bag which hung upon her arm by a heavy chain, and shut up like a bite.
There was one pilgrim, a quiet pockmarked little woman of fifty called Theodosia, who for over thirty years had gone about barefoot and worn heavy chains.
But those heavy chains precluded any such possibility.
The base of each staff was surrounded by short posts, painted white and connected by heavy chains.
Very soon you would have thought from the sound on the Pequod's decks, that all hands were preparing to cast anchor in the deep; for heavy chains are being dragged along the deck, and thrust rattling out of the port-holes.
After a pause of a moment, he proceeded, in his stately way, to the door, drew back the ponderous bolts, unhooked the heavy chains, and began to draw it open.
These conducted her through the doorway which the blacks, pulling upon heavy chains, closed behind them.