In this study, the scientists found that hematopoietic stem cells
and neutrophils migration depends on the megakaryocyte size and distributions.
Omidubicel is designed to enhance the life-saving benefits of hematopoietic stem cell
(bone marrow) transplant.
'Half-matched hematopoietic stem cell
transplants usually elicit strong rejection from the recipient's body,' said Wang, director of the hospital's hematology department.
Zhu, "Current uses and outcome of hematopoietic stem cell
transplantation: CIBMTR summary slides," http://www.cibmtr.org, 2015.
Wilson et al., "Hematopoietic stem cell
function and survival depend on c-Myc and NMyc activity," Cell Stem Cell, vol.
Reynaud and collaborators, including first author and post-doctoral research fellow Jung-Mi Lee, show that obesity related stresses alter the cellular architecture of the hematopoietic stem cell
compartment and reduce its long-term functional fitness.
After hematopoietic stem cell
transplantation, quality of life may be adversely affected because of autoimmune and hematologic complications, pulmonary diseases, cardiovascular diseases, ocular complications, musculoskeletal problems, oral mucosa and dental problems, genitourinary system problems, gastrointestinal and hepatic complications, metabolic problems, nervous system disorders, secondary malignancies, and psychosocial problems [3-5].
Haight, "The ethics of a proposed study of hematopoietic stem cell
transplant for children with 'less severe' sickle cell disease," Blood, vol.
The researchers measured vitamin C levels in 79 healthy volunteers and 42 hematology-oncology patients treated with chemotherapy or hematopoietic stem cell
2013), and loss of that strict regulation via TCDD exposure could affect hematopoietic stem cell
The report provides comprehensive information on the therapeutics under development for Hematopoietic Stem Cell
Transplantation, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.