In this study, the scientists found that
hematopoietic stem cells and neutrophils migration depends on the megakaryocyte size and distributions.
Omidubicel is designed to enhance the life-saving benefits of
hematopoietic stem cell (bone marrow) transplant.
'Half-matched
hematopoietic stem cell transplants usually elicit strong rejection from the recipient's body,' said Wang, director of the hospital's hematology department.
Zhu, "Current uses and outcome of
hematopoietic stem cell transplantation: CIBMTR summary slides," http://www.cibmtr.org, 2015.
Wilson et al., "
Hematopoietic stem cell function and survival depend on c-Myc and NMyc activity," Cell Stem Cell, vol.
Reynaud and collaborators, including first author and post-doctoral research fellow Jung-Mi Lee, show that obesity related stresses alter the cellular architecture of the
hematopoietic stem cell compartment and reduce its long-term functional fitness.
After
hematopoietic stem cell transplantation, quality of life may be adversely affected because of autoimmune and hematologic complications, pulmonary diseases, cardiovascular diseases, ocular complications, musculoskeletal problems, oral mucosa and dental problems, genitourinary system problems, gastrointestinal and hepatic complications, metabolic problems, nervous system disorders, secondary malignancies, and psychosocial problems [3-5].
Haight, "The ethics of a proposed study of
hematopoietic stem cell transplant for children with 'less severe' sickle cell disease," Blood, vol.
The researchers measured vitamin C levels in 79 healthy volunteers and 42 hematology-oncology patients treated with chemotherapy or
hematopoietic stem cell transplantation.
2013), and loss of that strict regulation via TCDD exposure could affect
hematopoietic stem cell renewal capacity.
The report provides comprehensive information on the therapeutics under development for
Hematopoietic Stem Cell Transplantation, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.