heme


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heme

 (hēm)
n.
A deep red, iron-containing compound, C34H32FeN4O4, that constitutes the nonprotein component of hemoglobin and certain other proteins.

[Short for hematin.]

heme

(him)

n.
an unstable, deep red, iron-containing blood pigment, C34H32N4O4Fe, obtained from hemoglobin.
[1920–25; shortening of hemoglobin]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.heme - a complex red organic pigment containing iron and other atoms to which oxygen binds
pigment - dry coloring material (especially a powder to be mixed with a liquid to produce paint, etc.)
haemoglobin, Hb, hemoglobin - a hemoprotein composed of globin and heme that gives red blood cells their characteristic color; function primarily to transport oxygen from the lungs to the body tissues; "fish have simpler hemoglobin than mammals"
myoglobin - a hemoprotein that receives oxygen from hemoglobin and stores it in the tissues until needed
cytochrome - (biochemistry) a class of hemoprotein whose principal biological function is electron transfer (especially in cellular respiration)
References in periodicals archive ?
Disruption of an active site hydrogen bond converts human heme oxygenase-1 into a peroxidase.
The antioxidative effect of whey proteins is mainly associated with beta-lactoglobulin and lactoferrin due to their ability to inactivate prooxidative heme proteins (ferrylmyoglobin) and to bind iron [14].
In addition to generation of ROS from free Hb, iron released from heme degradation can result in the generation of additional ROS resulting in cellular damage.
These authors further showed that a defect in iron recycling accounts for dysregulation of iron homeostasis in human with heme oxygenase-1 deficiency [17].
"When you breathe in air, the heme molecule absorbs oxygen from the air to your lungs, and when you exhale, it transports carbon dioxide out," Taylor writes.
The MPO light chain was not included in the alignment because it does not contain heme and the overall sequence similarity is even lower.
ELISA: Enzyme-linked immunosorbent assays GI: Gastrointestinal HO: Heme oxygenase IR: Immunoreactive nNOS: Neuronal nitric oxide synthase PB: Phosphate buffer ROS: Reactive oxygen species STZ: Streptozotocin.
However, it has been reported that hepatocyte dysfunction could occur as a result of accumulation of free heme and high levels of serum TNF-[alpha] during malaria [23,24].
Mishra, "The heme oxygenase system suppresses perirenal visceral adiposity, abates renal inflammation and ameliorates diabetic nephropathy in Zucker diabetic fatty rats," PLoS One, vol.
However, he adds, cooking in water "would not necessarily remove the carcinogenic potential of, for example, heme iron."
Under the company's Molecular Oncology and Cellular Tumor Marker permit, the HEME FISH-based assays was awarded approval for detection of amplifications or rearrangements of DNA in several hematologic cancers, including leukemias, lymphomas and myelomas in order to form a diagnosis and/or to evaluate prognosis or remission of disease.
Heme oxygenase-1 immunostaining was weakly present in tubules of both SHAM and RP groups (Fig.