zygosity

(redirected from hemizygote)
Also found in: Medical.
Related to hemizygote: heterozygous, homozygote, homozygous

zy·gos·i·ty

 (zī-gŏs′ĭ-tē)
n.
The genetic condition of a zygote, especially with respect to its being a homozygote or a heterozygote.

zygosity

(zaɪˈɡɒsɪtɪ)
n
(Genetics) genetics the similarity or differences between DNA sequences on the chromosomes of a fertilized egg

zy•gos•i•ty

(zaɪˈgɒs ɪ ti, zɪ-)

n.
1. the characterization of a hereditary trait in an individual according to whether the gene pairs for the trait are homozygous or heterozygous.
2. the characterization of twins, triplets, etc., according to whether they are monozygotic or dizygotic.
[1945–50; probably derivative of -zygous (see heterozygous), on the model of viscous: viscosity, etc.]
References in periodicals archive ?
It may be found in both males and females but male hemizygote and female homozygote are affected more severely than female heterozygote.
Glucose-6-phosphate dehydrogenase enzyme activity in normal, hemizygote and heterozygote Kelantanese Malays.
To estimate the imprecision of the new method, control plasma was supplemented with lysoGb3 at a high concentration comparable to concentrations found in hemizygote Fabry patients as well as a low concentration comparable to concentrations in heterozygotes.
No homozygote advantage was found in lines with the cryIA(c) gene insert; instead, there was a tendency for a hemizygote advantage in two out of three backgrounds.
3) deficiency (McKusick 31125) causes severe disease in male hemizygote neonates, and neonates with this deficiency present with lethargy, vomiting, coma, and hyperammonemia.
Immunoquantification of a-galactosidase in DBS for the analysis of Fabry disease showed that all 13 Fabry hemizygotes fell below the range of protein concentration for 71 control DBS (50).
Cardiac involvement in Fabry's is frequent and is more serious in hemizygotes.
DHs are also a powerful tool in transgenesis, to avoid hemizygotes and save time and resources in the production of plants transformed with the transgene in both homologous chromosomes.
A study of more than 2000 Gambian and Kenyan children found that the common African form of G-6-PD deficiency (G-6-PDA-) is associated with about 50% reduced risk of severe malaria in female heterozygotes and in male hemizygotes.
2:3] lines were either all homozygous for the CP4 EPSPS transgene or a combination of homozygotes and hemizygotes.
The magnitudes of QTL effects estimated in this study refer to the difference between a homozygote and a heterozygote for autosomal QTL or the difference between the two hemizygotes for X-linked QTL.