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Related to hemizygote: heterozygous, homozygote, homozygous


The genetic condition of a zygote, especially with respect to its being a homozygote or a heterozygote.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Genetics) genetics the similarity or differences between DNA sequences on the chromosomes of a fertilized egg
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(zaɪˈgɒs ɪ ti, zɪ-)

1. the characterization of a hereditary trait in an individual according to whether the gene pairs for the trait are homozygous or heterozygous.
2. the characterization of twins, triplets, etc., according to whether they are monozygotic or dizygotic.
[1945–50; probably derivative of -zygous (see heterozygous), on the model of viscous: viscosity, etc.]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
When the sample was separated by sex, the association of aggressive behavior remained among hemizygote males with the G allele (P=0.022).
(a) Patient sequence (hemizygote), a missense mutation occurred in the patient's gene, G to C.
Androgen insensitivity syndrome was diagnosed with hemizygote p.L863F (c.2587C > T) mutation.
It may be found in both males and females but male hemizygote and female homozygote are affected more severely than female heterozygote.3
Glucose-6-phosphate dehydrogenase enzyme activity in normal, hemizygote and heterozygote Kelantanese Malays.
To estimate the imprecision of the new method, control plasma was supplemented with lysoGb3 at a high concentration comparable to concentrations found in hemizygote Fabry patients as well as a low concentration comparable to concentrations in heterozygotes.
In these populations, homozygotes produced 14% more CryIA protein than hemizygotes. No homozygote advantage was found in lines with the cryIA(c) gene insert; instead, there was a tendency for a hemizygote advantage in two out of three backgrounds.
X-linked ornithine carbamoyltransferase (OCT; EC deficiency (McKusick 31125) causes severe disease in male hemizygote neonates, and neonates with this deficiency present with lethargy, vomiting, coma, and hyperammonemia.
Desnick, and etal., "Fabry: disease: enzymatic diagnosis of hemizygotes and heterozygotes alpha-galactosidase activities in plasma, serum, urine, and leukocytes," Journal of Laboratory and Clinical Medicine, vol.
Immunoquantification of a-galactosidase in DBS for the analysis of Fabry disease showed that all 13 Fabry hemizygotes fell below the range of protein concentration for 71 control DBS (50).