It may be found in both males and females but male hemizygote
and female homozygote are affected more severely than female heterozygote.
Glucose-6-phosphate dehydrogenase enzyme activity in normal, hemizygote
and heterozygote Kelantanese Malays.
To estimate the imprecision of the new method, control plasma was supplemented with lysoGb3 at a high concentration comparable to concentrations found in hemizygote
Fabry patients as well as a low concentration comparable to concentrations in heterozygotes.
No homozygote advantage was found in lines with the cryIA(c) gene insert; instead, there was a tendency for a hemizygote
advantage in two out of three backgrounds.
3) deficiency (McKusick 31125) causes severe disease in male hemizygote
neonates, and neonates with this deficiency present with lethargy, vomiting, coma, and hyperammonemia.
are considered equivalent to female homozygous states.
Immunoquantification of a-galactosidase in DBS for the analysis of Fabry disease showed that all 13 Fabry hemizygotes
fell below the range of protein concentration for 71 control DBS (50).
Cardiac involvement in Fabry's is frequent and is more serious in hemizygotes
DHs are also a powerful tool in transgenesis, to avoid hemizygotes
and save time and resources in the production of plants transformed with the transgene in both homologous chromosomes.
A study of more than 2000 Gambian and Kenyan children found that the common African form of G-6-PD deficiency (G-6-PDA-) is associated with about 50% reduced risk of severe malaria in female heterozygotes and in male hemizygotes
2:3] lines were either all homozygous for the CP4 EPSPS transgene or a combination of homozygotes and hemizygotes
The magnitudes of QTL effects estimated in this study refer to the difference between a homozygote and a heterozygote for autosomal QTL or the difference between the two hemizygotes
for X-linked QTL.