hemizygous


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hemizygous

(ˌhɛmɪˈzaɪɡəs)
adj
(Genetics) genetics (of a chromosome or gene) not having a homologue; not paired in a diploid cell
Translations
hemizygot
References in periodicals archive ?
According to these authors, if a resistance gene arises by mutation in a population, regardless of its intrinsic dominance or recessiveness, it can be exposed to selection from the outset in haploid males, as they are hemizygous, then accelerating resistance development.
(Some among you may note there's another possibility, hemizygous deletion.
Five patients from two different families had this mutation as homozygous and two patients from the same family had hemizygous inheritance as a part of compound heterozygous mutation.
Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw.
Molecular genetic analysis was performed for suspected MD and a hemizygous mutation (p.
Its genetic etiology affects the expression of the Proteolipidic Protein type 1 (3,4), varying from hemizygous mutations to gene dosage alterations of the PLP1 (Xq22).
Another advantage to this technique over polymerase chain reaction-based assays is the ability to identify homozygous and hemizygous deletions.
The GLA gene, which encodes [alpha]-galA, is located on the X-chromosome (Xq22.1), whereby practically all men carrying a genetic mutation (hemizygous) develop the disease, while women (heterozygotes) exhibit a wide variability in the severity of their phenotype, mainly due to the random X-chromosomes inactivation in each of their cells (Lyon hypothesis) [4].
Disease presentation of hemizygous males occurs more often as the classical type early in childhood or adolescence with typical symptoms, while heterozygous females can be affected as classical types, although the range of symptoms varies widely [2, 4].
Chen et al., "A severe case of hyperinsulinism due to hemizygous activating mutation of glutamate dehydrogenase," Pediatric Diabetes, vol.