hemizygous


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hemizygous

(ˌhɛmɪˈzaɪɡəs)
adj
(Genetics) genetics (of a chromosome or gene) not having a homologue; not paired in a diploid cell
Translations
hemizygot
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References in periodicals archive ?
Among the first generation of these mouse pairs, the most severe AI appeared on the incisors of hemizygous (AmelxX*/Y) mutant male mice.
Immunohistochemical Study of Amelogenin Binding Proteins in an Amelogenin Point Mutation Mouse/Estudio Inmunohistoquimico de Proteinas de Union de la Amelogenina en un Raton con Mutacion Puntual de Amelogenina
According to these authors, if a resistance gene arises by mutation in a population, regardless of its intrinsic dominance or recessiveness, it can be exposed to selection from the outset in haploid males, as they are hemizygous, then accelerating resistance development.
Avances en la epidemiologia de los begomovirus y su vector Bemisia tabaci en Costa Rica
(Some among you may note there's another possibility, hemizygous deletion.
Microsatellites and VNTR typing in clinical settings
Five patients from two different families had this mutation as homozygous and two patients from the same family had hemizygous inheritance as a part of compound heterozygous mutation.
Genetic and Clinical Characteristics of Patients with Vitamin D Dependent Rickets Type 1A
Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw.
Genome analysis of Yucatan miniature pigs to assess their potential as biomedical model animals
Molecular genetic analysis was performed for suspected MD and a hemizygous mutation (p.
De Novo Mutation in ATP7A Gene with Severe Menkes Disease
Its genetic etiology affects the expression of the Proteolipidic Protein type 1 (3,4), varying from hemizygous mutations to gene dosage alterations of the PLP1 (Xq22).
Clinical and mutational spectrum of Colombian patients with Pelizaeus Merzbacher Disease/Heterogeneidad clinica y mutacional en pacientes colombianos con Pelizaeus Merzbacher
Another advantage to this technique over polymerase chain reaction-based assays is the ability to identify homozygous and hemizygous deletions.
Guidelines for Pathologic Diagnosis of Malignant Mesothelioma: 2017 Update of the Consensus Statement From the International Mesothelioma Interest Group
The GLA gene, which encodes [alpha]-galA, is located on the X-chromosome (Xq22.1), whereby practically all men carrying a genetic mutation (hemizygous) develop the disease, while women (heterozygotes) exhibit a wide variability in the severity of their phenotype, mainly due to the random X-chromosomes inactivation in each of their cells (Lyon hypothesis) [4].
Major Organic Involvement in Women with Fabry Disease in Argentina
Disease presentation of hemizygous males occurs more often as the classical type early in childhood or adolescence with typical symptoms, while heterozygous females can be affected as classical types, although the range of symptoms varies widely [2, 4].
Time of Anderson-Fabry Disease Detection and Cardiovascular Presentation
A hemizygous c.31C>T(p.Arg11Ter) mutation was found in CD40LG gene.
An X-Linked Hyper-IgM Patient Followed Successfully for 23 Years without Hematopoietic Stem Cell Transplantation
Chen et al., "A severe case of hyperinsulinism due to hemizygous activating mutation of glutamate dehydrogenase," Pediatric Diabetes, vol.
Clinical and Molecular Spectrum of Glutamate Dehydrogenase Gene Defects in 26 Chinese Congenital Hyperinsulinemia Patients

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