hemochromatosis


Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia.

he·mo·chro·ma·to·sis

 (hē′mə-krō′mə-tō′sĭs)
n.
A condition, usually hereditary, in which excessive amounts of iron accumulate in body tissues, characterized by fatigue, joint pain, and bronze or gray pigmentation of the skin, and if untreated, leading to complications such as liver dysfunction and diabetes mellitus.

he•mo•chro•ma•to•sis

(ˌhi məˌkroʊ məˈtoʊ sɪs)

n.
a disorder of iron metabolism manifested by bronzed skin due to excessive iron absorption, leading to joint pain, diabetes, and liver damage if iron concentration is not reduced.
[1895–1900; hemo- + Greek chrōmat-, s. of chrôma color + -osis]
he`mo•chro`ma•tot′ic (-ˈtɒt ɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.hemochromatosis - pathology in which iron accumulates in the tissues; characterized by bronzed skin and enlarged liver and diabetes mellitus and abnormalities of the pancreas and the joints
pathology - any deviation from a healthy or normal condition
classic hemochromatosis, idiopathic hemochromatosis - inherited form of hemochromatosis
acquired hemochromatosis - hemochromatosis resulting from repeated transfusions or from excessive intake of foods containing iron
Translations

he·mo·chro·ma·to·sis

[MIM*235200]
n. hemocromatosis, trastorno del metabolismo férrico acompañado por exceso de depósitos de hierro en los tejidos que causa anomalías de pigmentación de la piel, cirrosis hepática y diabetes.

hemochromatosis

n hemocromatosis f
References in periodicals archive ?
DIC would be unusual with a normal platelet count, and, although cirrhosis is a complication of hemochromatosis (2), factor V should also be decreased (3).
Additionally, the report provides an overview of key players involved in therapeutic development for Hemochromatosis and features dormant and discontinued projects.
DISCUSSION: Hereditary hemochromatosis is a recessive autosomal genetic disorder that alters a protein involved in the regulation of iron absorption.
In patients with genetic hemochromatosis, two problems exist simultaneously: I) a disproportionately large amount of iron is absorbed from the gastrointestinal tract (i.
Based on our patient's complaints of fatigue, weakness, arthralgia, and amenorrhea, as well as her abnormal iron levels, we suspected hereditary hemochromatosis (HH).
Strikingly, the distal interphalangeal (DIP) and PIP joints were intact, and hook-like osteophytic formations on the heads of the metacarpal bones were seen, which is typical of hemochromatosis.
The gene most responsible for hemochromatosis, HFE, makes a protein that helps control how much iron the intestinal tract absorbs from food and supplements.
Another tells of Kay Aull who found out that her father (and other members of her family) suffered from hereditary hemochromatosis.
Hemochromatosis is a genetic disorder of iron storage that results in excessive iron deposition in the parenchymal cells of the body.
A postmortem diagnosis of hereditary hemochromatosis was made on the basis of histopathologic, laboratory, and genetic testing.
5) The unique involvement of the central nervous system (CNS) distinguishes aceruloplasminemia from other iron or paramagnetic element storage disorders including hemochromatosis, Hallervorden-Spatz, and Wilson's disease.
Polymorphisms in the hemochromatosis gene (HFE) have been shown to modify the impact of cumulative lead exposure on measures of adult cognition and cardiac function.