hemolysis


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he·mol·y·sis

 (hĭ-mŏl′ĭ-sĭs, hē′mə-lī′sĭs)
n.
The destruction or dissolution of red blood cells, with subsequent release of hemoglobin.

he′mo·lyt′ic (hē′mə-lĭt′ĭk) adj.

he•mol•y•sis

(hɪˈmɒl ə sɪs)

n.
the breaking down of red blood cells with liberation of hemoglobin.
he•mo•lyt•ic (ˌhi məˈlɪt ɪk) adj.

hemolysis, haemolysis

the breaking down of erythrocytes with liberation of hemoglobin in the blood. — hemolytic, haemolytic, adj.
See also: Blood and Blood Vessels
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.hemolysis - lysis of erythrocytes with the release of hemoglobin
lysis - (biochemistry) dissolution or destruction of cells such as blood cells or bacteria
Translations

he·mol·y·sis

n. hemólisis, ruptura de eritrocitos con liberación de hemoglobina en el plasma;
immune ______ inmune;
venom ______ venenosa.

hemolysis

n hemólisis f
References in periodicals archive ?
Alexion ) announced that the pivotal Phase 3 study of ALXN1210, the company's investigational long-acting C5 complement inhibitor, demonstrated non-inferiority to Soliris in complement inhibitor treatment-naive patients with paroxysmal nocturnal hemoglobinuria based on the co-primary endpoints of transfusion avoidance and normalization of lactate dehydrogenase levels, a direct marker of complement-mediated hemolysis in PNH.
The other main type of compatibility test, the DAT, is typically used to diagnose causes of hemolysis, such as transfusion-related hemolysis, hemolytic disease of the fetus and newborn, autoimmune hemolytic anemia, and drug-induced immune hemolysis.
Hemolysis During Hemodialysis: Etiology, Identification, Interventions, and Acute and Long-Term Sequalae
By blocking the amplification loop of the complement alternative pathway, ACH-4471 has the potential to control intravascular hemolysis as well as prevent the development of extravascular hemolysis," said Professor Peter Browett, BMedSci, MBChB, FRACP, FRCPA; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.
It is approved in the US, European Union, Japan and other countries as the first and only treatment for patients with paroxysmal nocturnal hemoglobinuria to reduce hemolysis.
A DAT can detect immunotargeting of transfused RBCs before hemolysis is clinically evident, or it can confirm the presence of an alloantibody in suspected hemolytic transfusion reactions.
coagulase, hemolysis [a (Hla), b, g (HLG), d], enterotoxins, toxic shock syndrome toxin (TST), exfoliatins and PVL) (Tomita and Kamio, 1997; Archer, 1998).
Unfortunately, there is a lack of data on streptococci for which true hemolysis is very important for identification and other medically important human bacteria.
Beyond such regulatory requirements, a 2012 CLSI guideline provides a resource available to assay manufacturers regarding what specific information regarding hemolysis might be published in an IFU (3).
Episodes of delayed hemolysis 2-6 weeks after treatment for severe malaria with intravenous artesunate have been observed in non-malaria-immune patients in Europe (2).
The prevalence of a hemolysis after PDA endocarditis is unknown.
It demonstrates plasma yield >40% from whole blood with little to no hemolysis, an issue common among many fibrous substrates.