The role of trace elements in hemopoiesis
and in the therapy of anemia, Department of Medicine, College of Medicine, University of Utah; 17, 4 (1956).
It transduces a multitude of signals for many cellular activities like hemopoiesis
, lactation, fertility and development of immature embryo, immunity and mammary gland etc.1,2,3
Request for quotations : 18 / 09-1 drugs affecting hemopoiesis
and blood (coagulation factor ix for patients with hemophilia before the age of 7 years)
The bone marrow is the major site of hemopoiesis
in adult humans. Hematinic drugs stimulate the erythropoietin to produce more blood cells during anemia and this has been demonstrated in medicinal plants. Herbal drugs or medicinal plants have developed a wide spectrum of biological activities.
In these malignancies uncontrolled abnormal cells proliferation occur due to genetic aberration which repress normal hemopoiesis
resulting in altered physiological activities.1,2 These defects might be of myleoid or lymphoid lineage.3
Myelodysplastic syndrome (MDS) is a heterogeneous group of diseases, caused by clonal stem cell disorders, with the specific sign of peripheral cytopenia due to ineffective hemopoiesis
with normal or increased cellularity of the bone marrow.
Proinflammatory cytokines are emerging as key regulators of steady-state and infection-driven hemopoiesis
. Recent findings contributed to highlight how HSPC fate could be dictated by inflammatory factors in the BM microenvironment as HSPCs may actively respond to danger signals and proinflammatory cytokines [4, 5].
Intercellular communication is vital to stem cell development (hemopoiesis
)," he added.
The location of hemopoiesis
in ascidians is still debated, which might be a consequence of the variety of developmental strategies observed among this clade (Brown and Swalla, 2012).
The bone marrow material showed adequate hemopoiesis
in all three hemopoietic cell lines.
Graves, "Isolation, characterization and functional activity of human marrow stromal progenitors in hemopoiesis
," Progress in Clinical and Biological Research, vol.
Cd exposure is related to nephropathy, lung cancer, osteoporosis, abnormal hemopoiesis
, and various others [11-13].