The lessons from the experience with radioprotectors world wide are that the animal studies using death of the irradiated animals as the end point is the most confirmatory, because the 30 days time period after lethal whole body irradiation clearly indicates the capacity of the drug, in test to modulate the recovery and regeneration of the gastrointestinal epithelium and the hemopoietic
progenitor cells in the bone marrow, the two most radiosensitive organs that are essential for sustenance of life.
Their data indicate that proliferation and/or differentiation processes of hemopoietic
stem cells are influenced by TCDD administered 5-6 weeks postpartum.
Flt-1 is also present on trophoblasts and macrophages, whereas KDR is present on hemopoietic
stem cells, megakaryocytes, and retinal cells.
Nerve growth factor promotes human hemopoietic
colony growth and differentiation.
Expression of Ang1 receptors on primitive hemopoietic
stem cells suggests that this factor may also be useful in regenerating blood cells -- as might be beneficial during chemotherapy -- as well as in forming blood vessels.
Lenocta has also been demonstrated to augment cytokine signaling and responses in hemopoietic
cell lines, which can enhance the body's immune system.
Our results strongly suggest that the dysfunction of the p53 gene, possibly caused by strong and repeated genetic and epigenetic effects of benzene on candidate leukemia cells, may induce fatal problems such as those of cell cycle checkpoint, apoptosis, and the DNA repair system, finally resulting in hemopoietic
The majority of all the cell type involved in the immune system is produced from common hemopoietic
stem cells of bone marrow.
mRNA for the cytokeratin family members, carcinoembryonic antigen, and mucin-1 (6, 10, 13, 14) is also produced by healthy epithelial cells in the hemopoietic
Lineage promiscuity in hemopoietic
differentiation and leukemia.
5,521,073 covering the gene that encodes the human Tie-2 ligand protein and a method of using the gene to make the Tie-2 ligand protein, a growth factor involved in blood vessel formation whose receptor is also present on hemopoietic
This achievement follows on from the establishment and opening of the most advanced stem cell bank, with the largest Umbilical Cord Blood Hemopoietic
Stem Cell Bank, in 2001.