Transfusional
hemosiderosis also affects people with sickle cell anemia, myelodysplastic syndromes, and other chronic anemias.
La
hemosiderosis pulmonar idiopatica (HPI) es una enfermedad poco frecuente, de etiologia desconocida, caracterizada por hemorragia pulmonar recurrente o cronica y acumulacion de hemosiderina en los pulmones.
The CDC published a further report in 2000, concluding that an association between Stachybotrys and pulmonary hemorrhage in infants was not proven ("Update: Pulmonary hemorrhage/
Hemosiderosis Among Infants--Cleveland, Ohio, 1993-1996," Morbidity & Mortality Weekly Report, Mar.
While scientific evidence connecting mold to health problems remains inconclusive, many believe mold may cause certain adverse health effects ranging from minor symptoms such as eye irritation, cough, runny nose, allergy and asthma to more severe health ailments such as Organic Dust Toxic Syndrome and pulmonary
hemosiderosis.
They reported that in 1993 there were 10 cases of acute pulmonary hemorrhage/
hemosiderosis in infants, some of whom died, that was thought to be linked to the mold Stachybotrys chartarum (also known as Stachybotrys atra) (Robbins and Morrell 2003).
Another histologic indicator of nutritional stress was the higher degree of
hemosiderosis (pigment in Kupffer cells).
In the initial stage of iron overload, referred to as
hemosiderosis, tissues remain anatomically and functionally normal.
The report concerned a cluster of 10 cases of pulmonary hemorrhage and
hemosiderosis in very young infants during 1993-1994 in Cleveland.
This includes speech, memory, and some motor function.[2] The risks of surgery include superficial
hemosiderosis, worsening of preexisting neurological deficits, cerebral hemorrhage, hydrocephalus, and infection.
Hence, due to this such patients are at a risk of developing
hemosiderosis. [5] Due to this reason, iron salts are rarely employed in the treatment of sickle cell anaemia.
(1) However, lifetime transfusion therapy causes iron overload and
hemosiderosis in different organs (i.e., heart, liver, kidneys) so that cardiac
hemosiderosis is the most common cause of death in these patients.