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 (hĕp′ə-tō-tŏk-sĭs′ĭ-tē, hĭ-păt′ō-)
1. The quality or condition of being toxic or destructive to the liver.
2. The capacity of a substance to have damaging effects on the liver.

hep′a·to·tox′ic (-tŏk′sĭk) adj.


(Medicine) damaging to the liver
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.hepatotoxic - toxic to the liver
toxic - of or relating to or caused by a toxin or poison; "suffering from exposure to toxic substances"
References in periodicals archive ?
Acetadote, administered intravenously within 8 to 10 hours after ingestion of a potentially hepatotoxic quantity of acetaminophen, is indicated to prevent or lessen hepatic injury.
Background: Because of the hepatotoxic, mutagenic, and cancerogenic effects of pyrrolizidine alkaloids (PAs) the German Federal Institute for Risk Assessment (BfR) recommends not to exceed a daily PA intake of 0.
Additionally, because chemotherapy may be hepatotoxic or nephrotoxic, baseline liver and renal function tests should almost always be performed.
Although silymarin is hepatoprotective in animal experiments and some human hepatotoxic exposures, its efficacy in ameliorating the symptoms of acute clinical hepatitis remains inconclusive.
Toxic effects occur when the amount taken exceeds the liver's capacity to metabolise the hepatotoxic metabolite.
The participants were not taking hepatotoxic medications, and there was no uncertainty as to the skin examination findings.
To complicate matters, the HIV/TB co-infected patient is often exposed to other potentially hepatotoxic drugs and is prone to conditions associated with liver injury.
Its toxicity is attributed to the presence of a hepatotoxic terpenoid known as atractyloside, a powerful inhibitor of cellular respiration and ATP synthesis.
Fluconazole, used for outpatient treatment of cryptococcal meningitis, is potentially hepatotoxic.
We decided to perform talc pleurodesis by MT with local anesthesia in order to avoid potential hepatotoxic effects caused by drugs used in general anesthesia.
This low kava dose was chosen based on the manufacturer's daily dose recommendation as well as a desire to avoid potential hepatotoxic effects in participants.
The authors report that hepatitis B virus (HBV) infection, use of hepatotoxic medicines, and microcystin exposure were associated with liver damage among the children in the study.