Intraoperative fluid therapy consisted of a continuous-rate infusion of a balanced electrolyte solution (10 mL/kg per hour) and bolus of hetastarch
(10 mL/kg; Vetstarch, Abbott Laboratories, North Chicago, IL, USA), administered via an intraosseous catheter (22gauge spinal needle) placed in the right distal ulna.
The search terms for HES solutions included hydroxyethyl starch, hetastarch
, HES, or 130/0.
The patient also received about 6 ml/kg 6% hetastarch
Consequently, for the past decade the Tactical Combat Casualty Care committee recommended Hextend, a hetastarch
based product in a balanced salt solution, as the fluid of choice for small volume resuscitation, with guidance to limit the total infusion to one liter based on the casualty's mental status or pulse character.
Wilkes NJ, Woolf R, Mutch M, Mallett SV, Peachey T, Stephens R, Mythen MG 2001 The effects of balanced versus saline-based hetastarch
and crystalloid solutions on acid-base and electrolyte status and gastric mucosal perfusion in elderly surgical patients Anesthesia & Analgesia 93 811-816
Changes in intracranial pressure, coagulation, and neurologic outcome after resuscitation from experimental traumatic brain injury with hetastarch
Metronidazole (10 mg/kg BID) and Hetastarch
(20 ml/kg/day IV) were administered for one day prior to the procedure.
Hextend (6% Hetastarch
in Lactated Electrolyte Injection) is BioTime's commercially-available blood plasma volume expander used to treat hypovolemia (low blood volume).
Common colloids include whole blood, packed red blood cells (RBCs), plasma, Hetastarch
(hydroxyethyl starch), and dextrans (Dextran 70 and Dextran 40).
Em relacao ao uso de expansores do plasma, BEAL (2005) recomenda o Hetastarch
a 6% (derivado da amilopectina) em dose de 5-20ml [kg.
Volume replacement can be accomplished with concurrent administration of crystalloid or other volume expanders, such as hetastarch
(Hespan) or albumin.
The patient had severe anemia and thrombocytopenia requiring albumin, hetastarch
, vitamin K, erythropoietin, and transfusions of packed red blood cells, fresh-frozen plasma, and platelets.