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A change or set of changes in the timing or duration of an organism's ontogenetic development compared with an ancestral species, resulting in morphological differences between ancestor and descendant.

[hetero- + Greek khronos, time + -y.]

het′e·ro·chron′ic, het′e·ro·chron′ous adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌhɛtərəʊˈkrɒnɪk) or


(Biology) biology occurring at different times or stages
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14.
Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites.
JM & AC: Tom Rando of Stanford University announced in 2005 that heterochronic (different stages of development) parabiosis, where two mice of different ages were conjoined by surgery, restored the livers and muscles of the older one.
Ruvkun, "Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C.
Morrison, "A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties," eLife, vol.
Slack et al., "Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA," Nature, vol.
This inhomogeneous rhythm is called heterochronic development, in this case it is presented that there are periods of slow development and others of intense development, according to (J.
These heterochronic parabiosis's experiments have elegantly demonstrated that exposing old tissues and organs to a young circulatory environment can rejuvenate tissue-specific stem cells, leading to a youthful state, which is characterized by functional and regenerative improvements [52, 54].
In this case, we report a case of SAM with heterochronic vessel rupture of the splenic and common hepatic arteries, treated by surgical intervention and coil embolization.