heterophile


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Related to heterophile: heterophile antigen

heterophile

(ˈhɛtərəˌfaɪl) or

heterophil

n
(Biology) a polymorphonuclear leukocyte in humans that may be stained with dyes
adj
(Biology) able to stain with specific dyes
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
Lyme, Bartonella henselae, and heterophile antibodies were also negative.
Lymphocytosis with numerous atypical lymphocytes and elevated liver enzymes are most often observed in conjunction with the detection of EBV-specific serologies or heterophile antibodies.
Treatment with polyethylene glycol precipitates large-molecular-weight compounds such as IgG and can help identify heterophile antibodies and antigen-bound antibodies.
The presence of heterophile antibodies in the serum can interfere with the assay and produce false-positive tests.
EBV IgG and IgM were positive, but heterophile assay and EBV PCR was negative (Table 1).
However, other factors not investigated in this work, such as age differences in sensitivity to RDT, rheumatoid factor cross-reacting in the blood [46], and cross-reactivity with heterophile antibodies [47], can be responsible for false positive result in RDT.
Early or failing intrauterine pregnancies, ectopic pregnancies, heterophile antibodies, and hCG-secreting tumors are examples of medical conditions that could initially present as PUL [2, 3].
A heterophile antibody test was negative, however, as were EBV titers.
A heterophile antibody test yielded a positive result the day after admission, and a clinical diagnosis of infectious mononucleosis was confirmed 7 days later with positive Epstein–Barr virus (EBV) serology-positive viral capsid antigen immunoglobulin M, negative viral capsid antigen immunoglobulin G (IgG), and EBV nuclear antigen IgG.
However, before making a decision on the need for definitive treatment, a diagnosis should be made to distinguish between transient thyroiditis in the recovery phase and non-thyroid disease with changes in the hormonal profile, (26) or even laboratory interference (heterophile antibodies).
Okouchi, "Antigen of "serum sickness" type of heterophile antibodies in human sera: identification as gangliosides with N glycolylneuraminic acid," Biochemical and Biophysical Research Communications, vol.
Her EBV viral capsid antigen (VCA) antibodies IgM and IgG were positive at 1.3 and >8.0, respectively; and her early antigen antibody, nuclear antigen antibody, and heterophile antibody were all negative, indicating acute primary infection (BioPlex 2200 EBV IgM and IgG Kits).