heterophile antibody


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Related to heterophile antibody: heterophile antigen
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Noun1.heterophile antibody - an antibody found in the blood of someone suffering from infectious mononucleosis
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
References in periodicals archive ?
A heterophile antibody test was negative, however, as were EBV titers.
A heterophile antibody test yielded a positive result the day after admission, and a clinical diagnosis of infectious mononucleosis was confirmed 7 days later with positive Epstein–Barr virus (EBV) serology-positive viral capsid antigen immunoglobulin M, negative viral capsid antigen immunoglobulin G (IgG), and EBV nuclear antigen IgG.
Testing for cTnT was repeated with the hs-cTnT assay after treatment with heterophile antibody blocking agents and remained increased.
Blood cultures, monospot test (a form of the heterophile antibody test for infectious mononucleosis due to Epstein-Barr virus), and serology for hepatitis viruses were all negative.
But it has the disadvantage that the test sera need to be absorbed free from heterophile antibody.
The sharing of antigens between rickettsia and proteus is the basis of this heterophile antibody test.
The presence of a heterophile antibody can interfere with immunoassay tests such as hCG.
The possibility of heterophile antibody interference was investigated with an HBT.
The diagnosis relies on atypical lymphocytes which resemble monocytes or on heterophile antibody tests which assess agglutination with sheep, guinea pig and horse red cells.
18) Without liver biopsy, EBV infection can be diagnosed based on clinical suspicion and proper laboratory data including EBV IgM antibody, positive monospot and heterophile antibody testing.
Heterophile antibody tests have similar specificity and are cheaper, but are less sensitive in children or in adults during the early days of the illness (SOR: C, based on validating cohort study).
In a patient with acute EBV mononucleosis, the heterophile antibody test will be positive, as will tests for IgM viral capsid antigen (VCA) and IgG VCA.