histaminergic


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histaminergic

(ˌhɪstəmɪˈnɜːdʒɪk)
adj
1. (Biochemistry) releasing histamine
2. (Biochemistry) activated by histamine
References in periodicals archive ?
Agonists (acetylcholine, histamine) and their appropriate antagonists (atropine, H1 blocker-pheniramine maleate) were used to evaluate the cholinergic and histaminergic mechanisms.
Ingrezza selectively inhibits VMAT2 with no appreciable binding affinity for VMAT1, dopaminergic (including D2), serotonergic, adrenergic, histaminergic, or muscarinic receptors.
The product is a selective histamine H3-receptor antagonist/inverse agonist that improves the activity of histaminergic neurons.
sup][126] In addition, cholinergic interneurons activated in LID were attenuated by inhibition of H2 histaminergic transmission in mouse models.
This result may be due to serotonin modulation as mentioned above or some other mechanisms including histaminergic receptors.
Based on the finding that clozapine in low dosages acts at 5-HT2A receptors, (7) pimavanserin was designed to be a potent 5-HT2A inverse agonist, with more than 5-fold higher selectivity over 5-HT2C receptors, and no appreciable affinity for other serotonergic, adrenergic, dopaminergic, muscarinic, or histaminergic receptors (8) (Table 2, page 83).
Atpyical antipsychotic medications induce changes in appetite and food intake, most likely because of interaction with serotonergic, histaminergic, and dopaminergic neurotransmitter systems inducing increase in appetite and food intake.
Mirtazapine antidepressant role depends on serotonin types 2A, 2C, and 3 receptors (5-HT2A/2C/3) antagonism and alpha2 adrenergic receptors antagonism; it also exerts histaminergic type 1 receptors (H1) antagonism (sedation and weight gain), alpha1 adrenergic receptors antagonism (orthostatic hypotension), and M1 antagonism (anticholinergic effects) [24].
Chewing stimulates the ventromedial hypothalamic nucleus of the satiety center and activates the histaminergic system, which may reduce appetite [5].
Pimavanserin is a nondopaminergic, selective serotonin 5-HT2a inverse agonist, also devoid of affinity for adrenergic, histaminergic, or muscarinic receptors [67, 68].
Nondopaminergic neurotransmitters and neuromediators include cholinergic, adenosinergic, glutamatergic, GABAergic, noradrenergic, serotonergic, opioidergic, and histaminergic systems (Table 2) [21].