system has been shown to modulate emotional memory through different receptors, including at least four distinct subtypes of G-protein coupled receptors (H1-H4) that mediate the biological effects of histamine (HA) (1).
* Over-the-counter drugs and supplements may exert neurologic effects via histaminergic
, muscarinic, glutamatergic, adrenergic, or serotonergic effects--all of which can alter brain chemistry and contribute to mental status changes.
Unlike other antidepressants, VEN does not inhibit monoamine oxidase (MAO) and does not change the activity of other receptors, such as adrenoreceptors, histaminergic
receptors, or muscarinic receptors.
Identification of additional histaminergic
neurons in Aplysia: improvement of single cell isolation techniques for in tandem physiological and chemical studies.
Histamine and Histaminergic
Receptors in Colorectal Cancer: From Basic Science to Evidence-based Medicine.
The Histamine acts as a neurotransmitter, or autacoid, whose histaminergic
neuronsthat remain active during night hours, depending on the type of receptor, may stimulate or inhibit the CNV or the peripheral nervous system in the stomach (Secretin cells), skin, lungs, or muscles.
In the brainstem, neurodegeneration within ascending arousal systems controls neurotransmission across several neuronal nuclei such as the noradrenergic locus coeruleus, noradrenergic dorsal motor nucleus of the vagus nerve, serotonergic dorsal raphe nucleus, histaminergic
tuberomammillary nucleus, and dopaminergic areas.
It also includes orexin neurons in the lateral hypothalamic area (LHA) and histaminergic
neurons in the tuberomammillary nucleus (TMN).
First, it modulates histaminergic
neurotransmission by partially agonizing the activity of the histamine H1 receptor.
Goehler, "Lipopolysaccharide suppresses activation of the tuberomammillary histaminergic
system concomitant with behavior: A novel target of immune-sensory pathways," Neuroscience, vol.
Quetiapine is an atypical antipsychotic that possesses low to moderate antagonist activity at multiple neurotransmitter receptors, including serotonergic 5-hydroxytryptamine (5-[HT.sub.2A]) receptors, dopaminergic ([D.sub.1] and [D.sub.2]) receptors, histaminergic
([H.sub.1]) receptors, and adrenergic [[alpha].sub.1] and [[alpha].sub.2] receptors, and partial agonism at 5-[HT.sub.1A] receptors .