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Related to histiocyte: Langerhans cell


A macrophage or dendritic cell that is usually immobile and is found in organs and tissues.

[Greek histion, web, diminutive of histos; see stā- in Indo-European roots + -cyte.]

his′ti·o·cyt′ic (-sĭt′ĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Physiology) physiol a macrophage that occurs in connective tissue
[C20: alteration of German histiozyt, from Greek histion a little web, from histos web + -cyte]
histiocytic adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.histiocyte - a macrophage that is found in connective tissue
connective tissue - tissue of mesodermal origin consisting of e.g. collagen fibroblasts and fatty cells; supports organs and fills spaces between them and forms tendons and ligaments
macrophage - a large phagocyte; some are fixed and other circulate in the blood stream
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
It is characterised by an abnormal increase in certain immune cells called histiocyte cells - which area form of white blood cells that help the immune system destroy foreign materials and fight infection.
The large neoplastic cells in CHL are positive for CD15 and CD30 with weakly positive PAX5, and negative for CD45 and histiocyte markers.
It involves overproduction of a type of white blood cell called a histiocyte. These cells accumulate, most often in lymph nodes, or glands to you and me.
Furthermore, there are previously published reports of lymphocyte and histiocyte abundance in cases of Sweet's Syndrome [6-9].
Rosai-Dorfman disease (RDD), also known as "sinus histiocytosis with massive lymphadenopathy," is a nonmalignant disease of histiocyte proliferation.
F: Immunohistochemically positive immunoreactivity with histiocyte marker CD68 in multinuclear giant cells (immunostains, original magnification x400).
HLH is a potentially fatal hyperinflammatory syndrome characterized by histiocyte proliferation and hemophagocytosis.
The criteria for the diagnosis of LCH defined by the Histiocyte Society Writing group is classical LCH histopathology confirmed by the presence of Birbeck granules on electron microscopy or by demonstration of CD1a on immunohistochemistry.
The patient met the diagnostic criteria of HLH described by the Histiocyte Society [2].
Similar to the morphologic findings of the presented case, diffuse infiltration of neoplastic B-cells, with or without histiocyte increase, with a background almost completely comprising of reactive small T-cells, is observed in T/HRBCL.8-10 Small reactive B-cells are quite rarely seen.10 Cytologic features of both inflammatory background and the neoplastic component should be distinguished by immunohistochemical examination.3,9
It involves overproduction of a type of white blood cell called a histiocyte.