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An anticholinergic drug derived from tropine, C16H21NO3, used in its bromide form to dilate the pupil of the eye and in combination with hydrocodone to prevent overdosage of that drug.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
These products include: Fluorescein Sodium & Benoxinate, Altacaine, Goniotaire, and Homatropine. Altaire is the only manufacturer of FDA Approved Fluorescein Sodium & Benoxinate and Fluorescein Sodium & Proparacaine.
The patient was treated with prednisolone acetate 1% and homatropine 2% topical eye drops (Sina Darou, Iran) every 6 hours and 8 hours, respectively, for 5 days till the anterior chamber reaction and the ciliary injection were resolved.
Postoperatively, patient was prescribed topical steroids (betamethasone 0.1%) and topical antibiotic (moxifloxacin 0.5%) and 2hourly/day and 1% homatropine twice a day for one week then tapered it according to progress.
A fixed dilated pupil occurred in 1 eye due to prolonged use of Homatropine after the operation in PK.
M2 EQUITYBITES-February 20, 2017-Perrigo awarded US FDA final approval for hydrocodone bitartrate and homatropine methylbromide oral solution
M2 PHARMA-February 20, 2017-Perrigo awarded US FDA final approval for hydrocodone bitartrate and homatropine methylbromide oral solution
They vary in potency and duration of action, with the effects of cyclopentolate hydrochloride 1% lasting up to 24 hours compared to homatropine hydrobromide or atropine sulfate whose effects can continue for up to three or seven days, respectively.
The patient was initially given topical 1% topical prednisolone acetate (every hour while awake) and 1% homatropine (2*/d).
This class includes four anticholinergic agents: atropine, cyclopentolate (Cyclogyl), homatropine, and tropicamide (Mydriacyl).
Although there are no reports of teratogenic effects from topical use, minor fetal malformations have been reported from systemic use of phenylephrine, atropine and homatropine, and there is relative contraindication for their ophthalmologic use.56 In the first three months of pregnancy, even their application for the purpose of examination is not recommended.
Several pharmaceutical products containing hydrocodone in combination with acetaminophen, aspirin, other NSAIDs, and homatropine are approved by the FDA for use as analgesics for pain relief and for the symptomatic relief of cough and upper respiratory symptoms associated with allergies and colds; and
A postmydriatic test was done after 3 days if retinoscopy had been done under homatropine and after 2 weeks if it had been done under atropine.