Comment: High plasma homocysteine
levels have been associated with depression.
The novel MaxDiscovery Homocysteine
Enzymatic Assay Kit employs simplified endpoint analysis to offer high sensitivity and low detection limits.
No one disputes that homocysteine
is toxic to our inner arterial lining.
More limited evidence suggests that exposure to Pb may increase plasma homocysteine
Vitamin B12 is an essential cofactor in homocysteinemeta bolisem to methionine and vitamin B6 by cystathionine 6 synthase converts homocysteine
to cystathionine .
Increased plasma homocysteine
concentrations produce deleterious effects via several mechanisms (1).
Plasma total homocysteine
status of vegetarians compared with omnivores: a systematic review and meta-analysis.
It was found that homocysteine
levels did not correlate with the risk of adenoma development in the total population; however, when a subgroup analysis by gender was done, it was found that a higher plasma homocysteine
concentration significantly increased the risk for adenoma formation in the female cohort.
Those with high homocysteine
levels were found to be 60% more likely to suffer from depression.
Now, some scientists think that excess homocysteine
may also be a factor in poor mental health and that nearly one in six cases of depression in the elderly could be avoided by using aspirin to lower levels in the blood.
Group sample sizes of 35 and 51 achieve 98% post-hoc power for homocysteine
Total plasma homocysteine
level was determined by the high-performance liquid chromatography method with fluorescence detection.