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 (hō′mə-sĭs′tə-ēn′, -ĭn, -tē-)
An amino acid, C4H9NO2S, not found in proteins, that is used by the body in cellular metabolism. Elevated concentrations in the blood are associated with an increased risk of heart disease.

[homo-, homologous with (from homologous) + cysteine.]


(Chemistry) an amino acid occurring as an intermediate in the metabolism of methionine. Elevated levels in the blood may indicate increased risk of cardiovascular disease
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Plasma levels of homocystine decreased by 83-88% regardless of pre-treatment level, and plasma homocysteine decreased by 71-83%, regardless of the pre-treatment level.
Concentrations of 6 other amino acids including alloisoleucine, homocystine, cystathionine, cystine, argininosuccinate, [alpha]-aminoadipic acid, were not detectable (< 1 [micro]mol/L) in blood spot extracts.
A hypercoaguability work up revealed normal levels of factor V leiden, protein C, proteins S, antithrombin III, and homocystine.
Homocystine levels, polymorphisms and the risk of ischemic stroke in young Asian Indians.
Various studies have suggested that alpha tocopherol protects the rats against various stressors like homocystine induced oxidative stress18 and nicotine induced damaging effects19.
For example, adequate nutrients could be measured in terms of improvement in disease markers such as homocystine (an amino acid believed to increase the risk of heart disease at elevated concentrations), and the prevention of chronic diseases such as osteoporosis (Wallace 2005).
Methylation of guanidoacetic acid by homocystine plus choline with rat liver slices.
Wilcken and Wilcken In 1976, Shown in the first clinical study supporting the theory that coronary artery disease (CAD) had a correlation with higher levels of homocystine.
To detect Hg(II) ion selectively, we modified (20,45) the surface of the gold nanoparticle with mercaptopropionic acid (MPA) and homocystine (bound to the gold nanoparticle surface through Au-S bond) and we added a chelating ligand 2,6-pyridinedicarboxylic acid (PDCA), to the solution.
Folate, vitamin B12, and homocystine in major depressive disorder.
The B vitamins, especially folic acid, have been associated with lowering blood levels of homocystine (an amino acid, which in high levels, is associated with heart disease, stroke, and fractures).