homolog


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hom·o·log

or hom·o·logue  (hŏm′ə-lôg′, -lŏg′, hō′mə-)
n.
Something that is homologous, as an organ, body part, or gene.

[French homologue, from Greek homologon, neuter of homologos, agreeing; see homologous.]
References in periodicals archive ?
Subsequently, the Drosophila protein armadillo was identified as a homolog of [beta]-catenin, not just in structure but also in function (Kemler, 1993).
A classifier in the remote homology detection problem allows predicting whether a given protein is a remote homolog of a specific family.
RAMALLAH, August 24, 2017 (WAFA) -- Three Palestinian judges from the Judicial Inspection Department of the High Judicial Council (HJC) together with two chief prosecutors from the Attorney General office concluded on Thursday a four-day study trip to the Homolog Institution in Romania, according to a EUPOL COPPS press release.
Beclin 1 is the human homolog of BEC-1, has been shown to be monoallelically deleted in up to 75 percent of human cancers.
Based on the autopsy and toxicological examination conducted on the victims, authorities said they tested positive for a designer drug known as methylenedioxymethamphetamine or MDMA methylene homolog and methylenedixy cathinone.
The most frequently affected genes are v-raf murine sarcoma viral oncogene homolog B (BRAF) and neuroblastoma Ras viral oncogene homolog (NRAS), which show mutations in up to 40% to 50% and 15% to 20% of melanomas, respectively.
Global Markets Direct's, 'Atypical Chemokine Receptor 3 (Chemokine Orphan Receptor 1 or G-Protein Coupled Receptor 159 or G-Protein Coupled Receptor RDC1 Homolog or GPR159 or CXCR7) - Pipeline Review, H1 2016', provides in depth analysis on Atypical Chemokine Receptor 3 (Chemokine Orphan Receptor 1 or G-Protein Coupled Receptor 159 or G-Protein Coupled Receptor RDC1 Homolog or GPR159 or CXCR7) targeted pipeline therapeutics.
United States-based Constellation Pharmaceuticals has commenced a Phase I clinical trial of CPI-1205, a new inhibitor of Enhancer of Zeste Homolog 2 (EZH2), in patients with earlier treated and progressive lymphomas, it was reported on Wednesday.
At the top of the significantly mutated genes list were well-known driver genes tumor protein p53 (TP53), Kirsten rat sarcoma viral oncogene homolog (KRAS), BRAF, neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS), phosphatase and tensin homolog (PTEN), isocitrate dehydrogenase 1 (NADP +), soluble (IDH1), phosphatidylinositol-4,5bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA), potassium channel, voltage gated Shab related subfamily B, member 2 (KCNB2), cyclin-dependent kinase inhibitor 2A (CDKN2A), and EGFR, which previously have been shown to be significantly mutated in cancer (11, 12).
Thanks to our work, we think the sex peptide signal goes to a region of the fly's brain that is the homolog of the hypothalamus, which has been know for many years to be central in controlling sexual receptivity in vertebrates," explained co-lead author Dr Mark Palfreyman of the Research Institute of Molecular Pathology in Vienna, Austria.
Mark Palfreyman, from Research Institute of Molecular Pathology in Vienna, expalined in another Neuron paper that according to them the sex peptide signal went to a region of the fly's brain that was the homolog of the hypothalamus, which has been know for many years to be central in controlling sexual receptivity in vertebrates.
RPA is a highly conserved protein in higher eukaryotic organisms, and a homolog of RFA found in the budding yeast, Saccharomyces cerevisiae.