Pairwise comparisons for multiple tests among the polymorphic loci showed significant linkage disequilibrium between loci (Table 3), while 8 loci showed significant evidence for the presence of null alleles (Cxan2, Cxan5, Cxan6, Cxan10,Cxan13, Cxan16, Cxan27, Cxan28) according to Bonferroni correction (p [less than or equal to] 0.05), which can indicate homozygosis
was assumed as one allele group, HLA-B*57 allele was the most frequent allele showing a protective effect against the risk for HIV infection in children.
All families who have confirmed patient diagnosed as (Hb S disease) homozygosis
It is believed CCR5A32 homozygosis
may increase the risk of HCV infection (14,15).
The CC homozygosis
of the -174G>C IL-6 polymorphism predicts a lower efficacy of rituximab therapy in rheumatoid arthritis.
A more recent study reported no p16INK4a mRNA in 50% of UMs, and aberrant methylation in homozygosis
was found in all the UMs that did not express p16INK4a mRNA, while no methylation was detected in the UMs that exhibited p16INK4a expression., The study provided convincing evidence that promoter methylation of p16INK4a -controlled expression of the gene, which can drastically affect cell growth, migration, and invasion in UM.
A deep vein thrombosis caused by 20209 C>T mutation in homozygosis
of the prothrombin gene in a Caucasian patient.
However we find some similarities to central Mexico, allele HLA-DRB1* 04 had tendency to increase the risk for RRMS, alone, in homozygosis
or when associated with HLA-DRB1* 15.
It can be said that there is a risk of decrease in the genetic variation in ex-situ conservation herd which is the result of the increasing consanguinity scaling up the homozygosis
. Diminishing productivity, ability to transform feed into meat, and resistance to environmental conditions and illness, and increasing number of deformations are some of the most important negative effects of decreasing genetic variation as a result of increasing homozygosis
(Karahan et al., 2007).
Akodon cursor (ACU) presents variation in diploid numbers (2n = 14 to 16) due to a complex rearrangement involving chromosomes 1 and 3, in which pericentric inversions followed by a centric fusion gave rise to a karyotype with 2n = 15 when in heterozygosis or 2n = 14 when in homozygosis
have demonstrated that lung transplanted patients that displayed homozygosis
for HLA-E*01:01 or HLA-E*01:03 alleles showed impaired overall survival as compared with patients displaying heterozygosis.
In this study we observed higher levels of oxidative stress before and after exercise in athletes bearing the mutated allele V16, either in heterozygosis or in homozygosis
, than in wild-type subjects, as shown by increased dROMs and AOPP and decreased BAP and free thiols.