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 (hō′mō-zī′gəs, -mə-, hŏm′ə-)
Having the same alleles at a particular gene locus on homologous chromosomes.

ho′mo·zy·gos′i·ty (-gŏs′ĭ-tē) n.
ho′mo·zy′gous·ly adv.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌhəʊməʊzaɪˈɡɒsɪtɪ; ˌhɒm-)
(Genetics) genetics the condition or fact of being homozygous
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.homozygosity - the state of being homozygous; having two identical alleles of the same gene
state - the way something is with respect to its main attributes; "the current state of knowledge"; "his state of health"; "in a weak financial state"
heterozygosity - the state of being heterozygous; having two different alleles of the same gene
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive ?
C282Y homozygosity should be suspected in patients showing biochemically elevated levels of%TS and serum Ferritin.
Sanger sequence heterozygosity image (mother, father, and brothers; above) and Sanger sequence homozygosity image of the patient (below).
Patients with ET and PMF show disease heterozygosity while PV shows homozygosity.10,17
The cross population extended haplotype homozygosity (Rsb) analyses were conducted among BH, BRH, and JB using the rehh package [17] for R software.
pylori-related chronic gastritis who carried the homozygous G/G genotype of MDM2 SNP309 and to investigate the association of MDM2 SNP309 G/G homozygosity with advanced colorectal neoplasia (CRN) susceptibility in the Thai population.
Results: SNP genotypes data analyses identified multiple regions of homozygosity on different chromosomes.
The molecular analysis identified homozygosity for a sequence alteration affecting the acceptor splice site of exon 22 (Intron 21: c.2380-1G), both parents were heterezygous for the same genetic aberration.
Homozygosity for mutation G212A of the gene for aspartoacylase is associated with atypical form of Canavan's disease.
Homozygosity for a Robertsonian Translocation (13q;14q) in an otherwise healthy 44, xy man with a history of repeated fetal losses.
Homozygosity mapping is based on the hypothesis that rare mutation is inherited from common ancestor to both parents, so that affected individuals are homozygous by decent for polymorphic markers close to disease gene loci.
Localization of the Netherton syndrome gene to chromosome 5q32, by linkage analysis and homozygosity mapping.
(1) HLA-Cw*0602 homozygosity hasbeen linked to streptococcal-associated psoriasis.