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A cell that is produced in the laboratory by fusing an antibody-producing lymphocyte (which does not readily divide) with a nonantibody-producing cancer cell (which divides rapidly). The hybridoma proliferates and produces a continuous supply of a specific monoclonal antibody.
(Biochemistry) a hybrid cell formed by the fusion of two different types of cell, esp one capable of producing antibodies, but of limited lifespan, fused with an immortal tumour cell
[C20: from hybrid + -oma]
hy•brid•o•ma(ˌhaɪ brɪˈdoʊ mə)
n., pl. -mas.
a hybrid cell made in the laboratory by fusing a normal cell with a cancer cell, usu. a myeloma or lymphoma, in order to combine desired features of each, as the ability of the cancer cell to multiply rapidly with the ability of the normal cell to dictate the production of a specific antibody.
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|Noun||1.||hybridoma - a hybrid cell resulting from the fusion of a lymphocyte and a tumor cell; used to culture a specific monoclonal antibody|
n. hibridoma, célula somática híbrida capaz de producir anticuerpos.