hydrazide


Also found in: Medical, Encyclopedia, Wikipedia.
Related to hydrazide: hydrazine, hydrochlorothiazide, Hydrazone

hy·dra·zide

 (hī′drə-zīd′)
n.
A hydrazine derivative of an oxyacid, usually a carboxylic acid.

hydrazide

(ˈhaɪdrəˌzaɪd)
n
(Chemistry) any of a class of chemical compounds that result when hydrogen in hydrazine or any of its derivatives is replaced by an acid radical
Mentioned in ?
References in periodicals archive ?
The thiadiazolate containing potassium based framework was synthesized by adding 2-(2-fluorobiphenyl-4-yl) propanoic acid hydrazide (1 mmol, 0.258 g) to an ice cooled alcoholic potassium hydroxide solution containing 2 mmoles (0.112 g) of KOH.
Benzoic acid hydrazide, 4-nitrobenzoic hydrazide, polyphosphoric acid, tolylene-2,4-diisocyanate (TDI), 3,3'-dimethoxy4,4'-biphenylene diisocyanate (DMBPI), 2-aminopyrimidine and N-phenyldiethanolamine were purchased from SigmaAldrich, MI.
Fourthly, compound 5 was obtained through the reaction of hydrazide with ethyl isothiocyanate in an ethanol media.
1-(5-(Hydrazinecarbonyl)pyridin-2-yl)-3-(4-nitrophenyl)urea (2) Yellow solid; Yield: 65%; MP: 274-275[degrees]C; IR ([v.sub.max] [cm.sup.-1]): 3338, 3221 (N-H), 3078 (=C-H stretching), 1712 (C=O urea), 1678 (C=O hydrazide), 1620 (C=N), 1562, 1510, 1491, 1431 (C=C, N[O.sub.2], N-H, C-N), 815 (=C-H).
Leucine acid hydrazide (3a) Rf=0.71(CH[Cl.sub.3]); yield 84%; thick syrup; IR (KBr u max [cm.sup.-1]): 3419 (N-H), 1625 (C=O).
A mixture of hydrazide 3 (2.11 g, 10 mmole), KOH (0.56 g, 10 mmole), carbon disulfide (0.76 g, 0.01 mole), and ethanol (30 ml) was heated for 10 h (TLC) under reflux.
Adriamycin immune conjugates, anti-parasitic proteinase inhibiting activity against Trypanosoma brucei, which is the major cause of sleeping sickness in people (Cafferey et al., 2002) antimyco-bacterial (Kucukguzel and Rollas, 2002) insecticidal and anti-leishmanial (Bernardino et al., 2006; Sawada et al., 2003) and distinctive derivatives of hydrazide of N-cyanoethyl likewise demonstrated activity against [beta]-glucuronidase catalyst (Khan et al., 2002).
(Selvakumar et al., 2011) Hydrazide 3 (0.05 mol) was dissolved in potassium hydroxide solution (0.56 g/100 mL ethanol).
Key statement: Provided is a rubber composition for a tire soft stiffener improved in a crack resistance and a low heat generation, wherein carbon black (A) contained in the rubber shows specific particle size distribution behavior in an aggregate mass distribution curve, and the composition contains at least one compound selected from carbon black coupling agents consisting of bismaleimide (B), alkylidene hydrazide (C), disulfane (D) and carboxylic hydrazide (E), and a heavy-duty tire produced by using the above rubber composition is further provided.
N-Acetylcarnosine and histidyl- hydrazide are potent agents for multitargeted ophthalmic therapy of senile cataracts and diabetic ocular complications.
One widely used coupling method involves site-specific immobilization of glycoproteins (enzymes, hormones, and/or antibodies) through their carbohydrate moieties on hydrazide solid supports [8,9].
Especially, the hydrazide chemistry has been widely used for labeling reducing end of carbohydrate (Scheme 1(a)).