The only established long-term therapy for SCD is hydroxyurea
, a pill approved more than a decade ago to treat complications stemming from the disease.
More than 40 per cent of sufferers being cared for at the Genetic Blood Disease Centre in Salmaniya Medical Complex (SMC) are now taking Hydroxyurea
, a chemotherapy drug with antiretroviral properties that was first made widely available in Bahrain earlier this year.
Studies proved the efficacy of hydroxyurea
medication in reducing the number of bouts of pain.
Contract awarded for 5-fluorauracilo vial 500mg, cisplatin multidose vial 10mg, albendazole tablet and suspension, hydroxyurea
500mg, acetylsalicylic acid and succinylcholine
The "much anticipated" guideline to help primary care and emergency clinicians improve the management of sickle cell disease includes a consensus treatment protocol for implementing hydroxyurea
therapy and more detailed guidance regarding longterm transfusion therapy, according to a summary report published in Journal of the American Medical Association.
(UH) is a chemical that is used for the treatment of this type of cancer in chemotherapy.
Jessen prescribed three different drugs, including the experimental cancer drug, hydroxyurea
, to be taken a total of eight times a day to keep the virus in check.
A 43-year-old male patient was diagnosed with chronic myelogenous leukemia (CML), and hydroxyurea
treatment was begun 3 months before consultation.
Treatments such as hydroxyurea
therapy, blood transfusion therapy and surgical management, hematopoietic stem cell transplant, opiate detoxification and rehabilitation will also be addressed.
Individuals with SCD will require lifelong prophylactic penicillin and folate and in some cases hydroxyurea
, which acts by increasing the concentration of fetal haemoglobin (HbF) and reduces painful episodes, acute chest syndrome and the need for blood transfusions.
Treatment has centered on cytoreduction by therapeutic phlebotomy and/or treatment with cytoreductive pharmaceuticals such as hydroxyurea
The drug, hydroxyurea
, reduced pain episodes and improved key blood measurements in the children studied, according to researchers.