Clinical Manifestations of ARDS Acute Exudative Phase Proliferative Phase Fibrotic Phase * Dyspnea * Increased work of * Profound breathing respiratory distress * Tachypnea * Dyspnea * Critically refractory hypoxemia * Tachycardia * Tachypnea * Cyanosis * Pallor * Tachycardia * Mental status change * Mild hypoxia * Refractory * White out (white hypoxemia lung) on chest x-ray * Respiratory * Respiratory * Pulmonary alkalosis alkalosis hypertension * Bilateral pulmonary * Increased bilateral * Right heart failure infiltrates on pulmonary * Dense fibrotic chest x-ray infiltrates tissue on chest x-ray * Diaphoresis * Pulmonary * Hypercarbia
hypertension * Right heart failure * Death * Pulmonary fibrosis * Hypercarbia
Sources: Arbour, 2017; Carlucci et al.
The main side-effect with topiramate was hypercarbia
(n=1), with the average dose of topiramate being 9 mg/kg/day, and the average duration of treatment was 30 days.
Intercostal retractions are minimum; grunting is intermittent, oxygen requirement < 40%, slight/absent hypercarbia
Autonomic dysfunction presents as labile hypertension, tachycardia and vasoconstriction, as well as sweating, bradycardia, cardiac arrhythmias, fever, hypotension and hypercarbia
6 Anaesthesia related risk factors for perioperative pulmonary hypertensive crisis are hypercarbia
, hypoxia, painful stimuli, acidosis and airway instrumentation, which leads to rapid increase in pulmonary vascular resistance.
The respiratory acidosis, hypercarbia
, and hypoxia were not, however, the major cause of her mental dysfunction.
In 1993, we recorded morphine concentrations at steady-state in 30 infants receiving intravenous morphine infusions after cardiac surgery, and found that a plasma morphine concentration of <20 ng/mL was associated with hypercarbia
in 15% versus 67% in those over 20 ng/mL independent of age.
The clinical significance of subcutaneous emphysema is development of hypercarbia
due to increased continuous C[O.
In the presence of difficulty at intubation, complications such as dental injury, laryngospasm, bronchospasm, and severe complications such as hypoxia, hypercarbia
, and death can occur as a result of multiple intubation attempts.
Four healthy individuals were scanned by ASL under normocarbia (partial end-tidal pressure values = 40 mmHg) and hypercarbia
(partial end-tidal pressure values = 50 mmHg) conditions.
So, global hypoxia and hypercarbia
can fully develop during ACA before resuscitation, and the cellular energy stores were critically depleting.
Other studies show that infants facing soft porous bedding rebreathe exhaled air in the enclosed space, which can lead to hypoxemia and hypercarbia
(Patel, Harris, & Thach, 2001).