The hematology disorders segment has been divided into thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, cryoglobulinemia, multiple myeloma, metabolic disorders, familial hypercholesterolaemia
(homozygous), and fulminant Wilson disease.
Ezetimibe for treating primary heterozygous-familial and non-familial hypercholesterolaemia
. Technology appraisal guidance [TA385].
The patient had a history of hypercholesterolaemia
and was on anti hypercholesterolaemics for the last 2 years.
Monogenic disorders causing low-density lipoprotein cholesterol (LDL-C) concentrations >5 mmol/L, such as heterozygous familial hypercholesterolaemia
(FH) or homozygous FH with LDL-C concentrations >13 mmol/L, confer much higher risk.
Warning sign: Knobbly knuckles Watch out for: High cholesterol Telltale lumps of cholesterol on top of the knuckles are one of the signs of a potentially fatal condition called familial hypercholesterolaemia
. The hard, yellowy bumps are particularly noticeable when you clench your fist.
"As a result, persistent concerns like diabetes, hypertension and hypercholesterolaemia
are all worse among my patients when they see me after Ramadan," he said.
The court while hearing suo moto notice pertaining to children suffering from familial hypercholesterolaemia
(FH) disease ordered Drug Regulatory Authority of Pakistan (DRAP) to register medicine of this disease.
'Genetic defects causing familial hypercholesterolaemia
: Identification of deletions and duplications in the LDL-receptor gene and summary of all mutations found in patients attending the Hammersmith Hospital Lipid Clinic', Atherosclerosis, 2007-09'.
The contract has been signed to expand Aegerion's exclusive licence agreement for Lojuxta (lomitapide), an approved treatment for adult patients with the rare cholesterol disorder Homozygous Familial Hypercholesterolaemia
(HoFH), into Russia and the Commonwealth of Independent States (CIS) and the non-EU Balkan states.
After my grandad died of a heart attack at 56, we discovered high cholesterol runs in my family - familial hypercholesterolaemia
in children and adolescents: gaining decades of life by optimizing detection and treatment.