hyperchromatism

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Related to hyperchromasia: dysplasia

hyperchromatism

the occurrence of unusually intense coloration. — hyperchromatic, adj.
See also: Color
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The dark appearance of the neoplastic cells is caused by nuclear enlargement, hyperchromasia, crowding, and stratification, in addition to variable degrees of cytoplasmic mucin depletion, resulting in a high nuclear to cytoplasmic ratio.
In addition, pathologists should always keep in mind that the reactive urothelium can show atypical cellular morphology and search additional features such as loss of polarity, nuclear hyperchromasia and high nucleus/cytoplasmic ratio before diagnosing dysplasia.
The PIN lesions were characterized by the presence of nuclear atypia (enlarged and elongated nuclei, hyperchromasia, prominent nucleoli) with or without aberrant cellular piling.
Panel E shows atypical ductal hyperplasia: these proliferations are characterised by a combination of architectural complexity with partially formed secondary lumens and mild nuclear hyperchromasia in the epithelial-cell population.
The most important diagnostic feature of cancer cells are anisonucleosis, anisocytosis, abnormal nuclear texture and nuclear hyperchromasia and abnormal N/C ratio.
The spindle cells lacked cytological atypia, mitosis, and nuclear hyperchromasia of sarcoma.
Some nuclei showed hyperchromasia, pleomorphism, and mitosis.
Diffuse-type tumours were characterised by linear cords of poorly cohesive or discohesive epithelial cells, with moderate to severe nuclear hyperchromasia and minimal clear to pale eosinophilic cytoplasm.
The fibrous septa contained scattered multinucleated giant cells, abundant hemosiderin, osteoid matrix or reactive bone, and spindled mononuclear cells with plump nuclei without hyperchromasia or significant increase in mitoses, consistent with an aneurysmal bone cyst (ABC) component (Figure 5(a)).
Bronchial biopsy of the tissue showed that the mass was arranged in small clusters and aggregates of cells with pink eosinophilic cytoplasm, uniformity of nuclei and mild hyperchromasia.
The islets were shrunken with atypical cellular changes, such as mild hyperchromasia, coarse chromatin and pyknosis (Fig.
Morphological Evaluation Criteria GROUPS CELL SHAPE NUCLEUS NUCLEUS S I Z E SIZE Control Small Round Hyperchromasia Prominent EGCG LD; Medium Oblong Hypochromasia Single EGC G HD TQ LD; TQ Large Irregular Multiple HD TA LD;TA Oval HD GROUPS CYTOPLASM STAIN Control Well-defined Coarse EGCG LD; Clusters Pink EGC G HD TQ LD; TQ Irregular Vacuoles HD TA LD;TA HD