hyperchromatism


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hyperchromatism

the occurrence of unusually intense coloration. — hyperchromatic, adj.
See also: Color
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PanIN 2 is a mucinous, epithelial flat, or papillary lesion with some nuclear abnormalities, including loss of polarity, crowding, enlargement, nuclear stratification, and hyperchromatism.
Cells have big nuclei with hyperchromatism and pleomorphism, and karyokinesis is increased (a, 20x).
Spindle cells showed some atypical features like cellular pleomorphism and nuclear hyperchromatism.
Parameters that were analyzed in the smear (both cytosmear and modified brush biopsy samples) included enlarged nuclei, nuclear pleomorphism, nuclear borders, nucleocytoplasmic (N/C) ratio, number of nuclei, binucleation, keratinization, tadpole forms, hyperchromatism, chromatin pattern, and distribution and discrepancy in N/C maturation.
Numerous keratin pearls and few mitotic figures with cellular and nuclear pleomorphism and hyperchromatism were also seen.
Tumor cells may invade the muscularis propria and even the adventitia without the presence of atypia or hyperchromatism.
The connective tissue stroma shows presence of areas of plump spindle shaped cells with mild nuclear and cellular pleomorphism along with nuclear hyperchromatism.
The findings in epithelium like presence of keratinization (non-keratinized/keratinized), thickness (atrophic/hyperplastic), dysplastic changes (mild/moderate/severe), inflammatory cells (acute/chronic), pleomorphism, mitotic figures and hyperchromatism were recorded.
Three cases showed focal atypia as basilar hyperplasia and hyperchromatism.
The endothelial cells that lining these channels display hyperchromatism and pleomorphism, have round or oval aspect, sometimes protuberant (Figures 7 and 8).