Ardelyx is also developing RDX013 -- a small molecule secretagogue -- for the treatment of hyperkalemia
These high effluxes of metabolites result in abnormal accumulation in the blood and exceed the capacity of renal clearance and results hyperkalemia
, hyperuricemia, hyperphosphatemia and secondary hypocalcemia.
While spironolactone increases the risk of hyperkalemia
, in patients with no preexisting renal disease under 50 years of age, monitoring is not necessary because there is little to no risk of clinical hyperkalemia
in these patients, she said.
More than 5mEq/L of serum potassium is called as Hyperkalemia
rarely appears among healthy individuals as potassium is well regulated by kidneys2.
among hospitalized patients and association between duration of hyperkalemia
But kidneys that don't function normally can allow potassium to build up, potentially triggering "hyperkalemia
" which causes nausea and leads to muscle weakness, tiredness, a slow pulse and an irregular heartbeat.
by Courtesy of BrandpointFor patients with hyperkalemia
, controlling potassium levels requires special attention to one's diet.
Presentations will include findings from some of the largest trials in broad patient populations with FARXIGA in type 2 diabetes, BRILINTA in patients with a history of heart attack, and in hyperkalemia
. Clinical trial results showing the safety and efficacy of FARXIGA vs.
Artificial Intelligence company AliveCor reported on Monday the receipt of US Food and Drug Administration breakthrough device status to expedite, assess and review the KardiaK Software Platform for screening of the elevated levels of blood potassium (hyperkalemia
) without requiring any blood from the patient.
Among the clinical scenarios of the cases are critical aortic stenosis, stress-induced cardiomyopathy (Takotsubo cardiomyopathy), multi-vessel disease: demand ischemia causing ST elevations, hyperkalemia
, and critical aortic stenosis.
Routine blood and urine tests were normal; however, persistent hyperkalemia
Initial lab findings were significant for a profound metabolic acidosis with an arterial pH of 6.55 (Figure 1), hyperglycemia (963 mg/dL), hydroxybuterate level greater than 8mmol/L, hyperkalemia
(7.6mmol/L), bicarbonate of 3.7 mEq/L, anion gap of 27 mEq/L, creatinine of 5.5 mg/dL, and a lactate of 5.25mmol/L.