In our study 50% (30/60) patients were found to be hyperlipidaemic
. Out of 30, 16 patients had raised VLDL, 9 patients had raised triglycerides and 5 patients had raised both VLDL and triglycerides.
In a randomised controlled trial (RCT), hypercholesterolaemic Iranian patients treated with 2 g of black seeds powder daily for four weeks had a significant decrease in TC, LDL-C and highly significant decrease in TG, but no significant effect on FBG (161), and administration of powdered seeds in a dose of 3 g/day along with garlic capsules for eight weeks to 30 healthy postmenopausal Emarati women significantly improved blood oxidants and antioxidants balance (162), whereas 19 postmenopausal hyperlipidaemic
Malaysian women and 15 with metabolic syndrome, treated with powdered seeds 1g daily after breakfast for two months showed no significant reduction in body weight but a significant fall in FBG, TC, LDL-C, and TG, and increased HDL-C (163,164).
Sterna, "Comparative pharmacokinetics and pharmacodynamics of propranolol and atenolol in normolipaemic and hyperlipidaemic
obese subjects," Biopharmaceutics and Drug Disposition, vol.
Akinniyi, "Total lipid profile and faecal cholesterol with aqueous fruit extract of solanum macrocarpum in triton-induced hyperlipidaemic
albino rats," Journal of Medicinal Plants Research, vol.
Skeaff et al., "A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic
subjects," European Journal of Clinical Nutrition, vol.
A systematic review of the epidemiology, pathophysiology and current management of hyperlipidaemic
Ginkgo biloba leaf extract (EGb 761) diminishes adriamycin-induced hyperlipidaemic
nephrotoxicity in rats: association with nitric oxide production.
Early en-face immunohistochemical staining in animal studies of atherosclerosis demonstrates the upregulation of VCAM-1 (vascular cell adhesion molecule-1) in turbulent flow sites in hyperlipidaemic
animals compared to wild-type animals .
Seylaz, "Effect of sympathectomy on the phenotype of smooth muscle cells of middle cerebral and ear arteries of hyperlipidaemic
rabbits," The Histochemical Journal, vol.
Rahman et al., "Lipid lowering effect of Cinnamomum zeylanicum in hyperlipidaemic
albino rabbits," Pakistan Journal of Pharmaceutical Sciences, vol.