hypernatraemia


Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to hypernatraemia: Hyponatraemia, Hyperkalaemia, Hypokalaemia

hypernatraemia

(ˌhaɪpənəˈtriːmɪə)
n
(Medicine) med Brit a heightened concentration of sodium in the blood
References in periodicals archive ?
37 62 Prior antibiotics before admis- sion (%) 32.4 16.1 0.059 Clinical status on admission Shock (%) 38.9 21.3 0.1753 Moderate dehydration (%) 44.4 57.4 0.1753 Oral thrush (%) 29.7 16.1 0.109 Lymphadenopathy (%) 40.5 11.3 0.00007 Hepatomegaly (%) 45.9 14.5 0.0005 Pneumonia (%) 27 14.5 0.126 Investigations Hyponatraemia (Na <130 mmol/l) (%) 32.4 27.4 0.596 Hypernatraemia (Na >145 mmol/l) (%) 16.2 19.7 0.6684 Hypokalaemia (K <3.5 mmol/l) (%) 51.4 46.8 0.653 Acidosis (CO2 <10 mmol/l) (%) 27 32.3 0.5837 Anion gap >20 mmol/l 30.3 37 0.512 Anaemia (Hb <10 g/dl) (%) 59.5 9.7 <0.005 * Pearson's chi-square test.
The main drawback of all these procedures is high additional sodium delivery due to combined infusion of trisodium citrate and sodium bicarbonate, which may lead to hypernatraemia and metabolic alkalosis.
Caution is advised with bicarbonate therapy since hypocalcaemia, hypernatraemia, systemic alkalosis and potential tetany are potential adverse effects.
On the fourth day the patient developed significant polyuria (150-450 ml/h) with a persistent hypernatraemia (maximum serum sodium 160 mmol/l).
Hypo- and hypernatraemia management should follow recommended guidelines; however, where ORT is possible, the process of rehydration usually allows metabolic homeostasis to be re-established.
Impaired level of consciousness was defined as a Glasgow Coma Scale <15, hypernatraemia as uncorrected serum sodium >150 mmol/l, hypokalaemia as serum potassium <3.5 mmol/l, hyperkalaemia as serum potassium >5.5 mmol/l, hypochloraemia as serum chloride <94 mmol/l, and hyperchloraemia as serum chloride >104 mol/l.
The authors propose that Peters' collapse was probably due to a combination of hyperthermia-induced fatigue which caused him to stop running; exercise-induced postural hypotension as a result of low peripheral vascular resistance; and combined cerebral effects of hyperthermia, hypertonic hypernatraemia associated with dehydration, and perhaps undiagnosed hypoglycaemia.
We propose that Peters' collapse was more likely due to a combination of hyperthermia-induced fatigue which caused him to stop running; exercise-associated postural hypotension as a result of a low peripheral vascular resistance immediately he stopped running; and combined cerebral effects of hyperthermia, hypertonic hypernatraemia associated with dehydration, and perhaps undiagnosed hypoglycaemia.
Effects of hypernatraemia in the central nervous system and its therapy in rats and rabbits.
If left untreated, persistent vomiting and diarrhea can result in heart failure caused by hypernatraemia (elevated blood sodium levels) as well as severe dehydration.
Hypernatraemia induced by sodium polystyrene sulphonate (KayexalateA(r)) in two extremely low birth weight newborns.