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An abnormal increase in the number of cells in a tissue or organ, with consequent enlargement of the part or organ.

hy′per·plas′tic (-plăs′tĭk) adj.


(Pathology) enlargement of a bodily organ or part resulting from an increase in the total number of cells. Compare hypertrophy
hyperplastic adj


(ˌhaɪ pərˈpleɪ ʒə, -ʒi ə, -zi ə)

1. abnormal multiplication of cells.
2. enlargement of a part due to an abnormal numerical increase of its cells.
hy`per•plas′tic (-ˈplæs tɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.hyperplasia - abnormal increase in number of cells
dysplasia - abnormal development (of organs or cells) or an abnormal structure resulting from such growth
benign prostatic hyperplasia, BPH - enlarged prostate; appears to be part of the natural aging process


n. hiperplasia, proliferación excesiva de células normales en un tejido.


n hiperplasia; benign prostatic— hiperplasia prostática benigna; congenital adrenal — hiperplasia suprarrenal congénita
References in periodicals archive ?
Conclusion: Loss of phophotase and tensin homologue expression was seen in a significant number of well differentiated endometrial adenocarcinomas and complex hyperplasias with atypia suggesting loss of PTEN expression as an early event in endometrial carcinogenesis.
However endometrial hyperplasias are among the most commonly over-diagnosed lesions in surgical pathology.
According to this classification hyperplasias are classified as simple, complex, with or without atypia [6, 7].
Endometrial hyperplasia is an important medical and social problem.
Investigators classified all benign breast biopsies as either nonproliferative, proliferative without atypia, or atypical hyperplasia, with the atypical hyperplasias being subclassified into atypical lobular hyperplasia or atypical ductal hyperplasia.
SAN ANTONIO -- All women with atypical hyperplasia in a benign breast biopsy are at significantly increased risk of developing breast cancer, but the magnitude of risk is greater when the pathology involves atypical lobular hyperplasia than it is with atypical ductal hyperplasia, according to data from the Nurses' Health Study.
No attempt was made to separate complex hyperplasias as those with and without nuclear atypia.
1) Hyperplasia is usually associated with exogenous estrogen stimulation, and thus, estrogen is considered as an endometrial carcinogen.
Among the various types of hyperplasias (total=22), simple hyperplasia (55%) was the commonest type followed by complex hyperplasia (36%) and atypical hyperplasia (9%).
Epitheliold hemangioendothelioma, multiple focal nodular hyperplasias, and cavernous hemangiomas of the liver.
Simple hyperplasia was the commonest finding among the types of hyperplasias in postmenopausal bleeding in the present study and study by Allison et al whereas Gredmark et al (14) and Reed et al (18) have noted complex hyperplasia as more common entity in postmenopausal age.
The main goal in evaluation of abnormal uterine bleeding in perimenopausal women is to exclude endometrial hyperplasia with atypia and endometrial carcinoma.