Erythema multiforme (EM) is a hypersensitivity reaction
of the skin to various agents with typical cutaneous and/or mucosal manifestations (1).The condition is often self-limiting but may be recurrent.
Fluoxetine is rarely associated with hypersensitivity reactions
. In one case, it was reported to be related with a severe systemic hypersensitivity reaction
including drug rash, eosinophilia, and systemic symptoms in a 4-year-old girl.
This type of delayed hypersensitivity reaction
is known as cell-mediated hypersensitivity.
In our patient, the diagnosis of hypersensitivity reaction
was made more difficult by the similarity of the symptomatology with the presenting signs of the vasculitic disease, mimicking a disease relapse.
Our case reported a rare hypersensitivity reaction
to dapsone, and hence, it is imperative for the physicians and dermatologists to have a watchful eye over the patients on dapsone to ensure timely diagnosis and appropriate management.
Herein we describe a case of hypersensitivity reaction
following sugammadex administration to a 3-year-old boy.
Premeditation with intravenous hydrocortisone and antihistamine can prevent serious hypersensitivity reaction
and should be routinely done.
Based on the clinical scenario, the patient's tentative diagnosis was ticagrelor-induced hypersensitivity reaction
with angioedema as this was the only new medication he was given (he was on daily maintenance aspirin for his CAD and previously tolerated a 1-year course of clopidogrel after drug-eluting stent implantation).
Azathioprine immune hypersensitivity reaction
is a rare adverse effect that has been reported in the literature relatively infrequently; however, the clinical presentation can often mimic sepsis [1, 2].
The nonimmunologic-type hypersensitivity reaction
directly activates mast cell degranulation without involving the activation of the immune system.
In the bovines evaluated in this investigation, PIA was believed to have occurred as a consequence of ingestion of wafer meal, which was easily inhaled by the cattle in its crushed state to result in a hypersensitivity reaction
in the pulmonary airways.
On May 1, 2017, FDA received an adverse event report concerning a 71-year-old male patient who developed a hypersensitivity reaction
after IV administration of ImprimisRx's compounded curcumin emulsion product.