The key to delivering a powerful sanitizing agent is to form hypochlorous acid
without elemental chlorine, which occurs at around neutral pH.
PuriCore is focused on the development of novel, prescription, topical treatments for inflammatory diseases with a differentiated mechanism of action that are based on formulations containing high concentrations of hypochlorous acid
The AOPP are dominated by 3-chlorotyrosine, dityrosine, and 3-nitrotyrosine modifications, which confirm the assumption that under in vivo conditions AOPP are generated by the action of hypochlorous acid
and chloramine produced by MPO.
NovaBay Pharmaceuticals is a clinical-stage biopharmaceutical company focused on addressing the unmet therapeutic needs of the global, topical anti-infective market with its two distinct product categories: Aganocide compounds, led by auriclosene, and its Hypochlorous Acid
Family of Products, led by NeutroPhase.
At body temperature, reactive chlorine in aqueous solution exists in two forms hypochlorite (OCL) and hypochlorous acid
Evaluation of hypochlorous acid
washes in the treatment of chronic venous leg ulcers.
The unit generates hypochlorous acid
to disinfect the microorganisms in ballast water that may have been taken on board when taking in ballast water.
The increase in rate of decolorization by higher production of hypochlorous acid
is also explained by oxidation potential values.
Exposing the ore and/or concentrate to an aqueous solution of chlorine-based oxidizing species in which the hypochlorous acid
comprises at least 10 mol% of the chlorine-based oxidizing species;
stress in Escherichia coli: Rresistance, DNA damage, and comparison with hydrogen peroxide stress.
Lipoate, or its reduced form, dihydrolipoate, reacts with reactive oxygen species such as superoxide radicals, hydroxyl radicals, hypochlorous acid
, peroxyl radicals, and singlet oxygen.
In the colon, but not the liver, neutrophils secreted hypochlorous acid
(also found in household bleach), which significantly damages proteins, DNA and RNA by adding a chlorine atom to them.