Ferring Pharmaceuticals has seen a positive outcome in the European Decentralised Procedure (DCP) for Testavan (transdermal testosterone gel 2%), a testosterone replacement therapy for adult male hypogonadism
, the private company announced on Thursday.
was diagnosed in patients with high basal FSH, LH, low testosterone and no response on hCG stimulation.
is defined by both low morning testosterone levels and symptoms of low testosterone.
IN THE 8 DECADES since the first clinical use of testosterone, its sole unequivocal indication is as replacement therapy for men with pathological hypogonadism
TODAY, 8 DECADES SINCE THE FIRST clinical use of testosterone, the sole unequivocal indication for testosterone treatment is as replacement therapy for men with pathological hypogonadism
The deficiency in release or action of GnRH leads to hypogonadotropic hypogonadism
(HH) characterized by low FSH, LH and testosterone (T) and absent or impaired sexual development at puberty.
GUANGZHOU, China, December 22, 2016 -- Male hypogonadism
is a condition that diminishes testosterone levels in approximately 30 percent of older men, but available therapies can produce serious side effects.
The Endocrine Society defines "androgen deficiency" as low serum testosterone (generally <280 ng/dL for healthy young men) along with signs and symptoms of hypogonadism
, including decreased sexual function; loss of axillary and/or pubic hair; low bone mineral density; loss of motivation and/or concentration; poor mood or depression; decline in cognitive function; and loss of muscle strength and work capacity (table 1).
The study included 189 men, among whom 107 had mild hypogonadism
and 87 had severe hypogonadism
as demonstrated by low total and free serum testosterone levels.
Global Markets Direct's, 'Secondary (Hypogonadotropic) Hypogonadism
- Pipeline Review, H1 2016', provides an overview of the Secondary (Hypogonadotropic) Hypogonadism
While the targets and molecular mechanisms underlying this phenomenon are still unknown, emerging evidence from experimental models of metabolic stress linked to hypogonadism
strongly suggests the potential role of perturbations of hypothalamic Kiss1/NKB neurons.
Now researchers say tests are needed to see if low testosterone levels, called hypogonadism
, trigger the cancer or are a result of it.