hypoxanthine


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hy·po·xan·thine

 (hī′pō-zăn′thēn′)
n.
A white powder, C5H4N4O, that is an intermediate in the metabolism of animal purines.

hypoxanthine

(ˌhaɪpəˈzænθiːn; -θɪn)
n
(Elements & Compounds) a white or colourless crystalline compound that is a breakdown product of nucleoproteins. Formula: C5H4N4O
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References in periodicals archive ?
reducing XDH converted to oxygen-reducing XOD, when tissue reperfused (molecular oxygen reintroduced into the tissues), oxygen interacts with hypoxanthine and XOD to produce ([O.
Despite these potential benefits of the blood cardioplegia, other studies suggested increased oxidative stress by either iron overload [40] or increase of hypoxanthine levels [97].
Enzyme(S) Substrate Effect Glycolytic enzymes Glycogen Lactic acid production resulting in pH drop Autolytic enzymes ADP, AMP, IMP Gradual Production involved in of Hypoxanthine nucleotide break down Cathepsins Proteins, peptides Softening of tissue Chymotrypsin, Proteins, peptides Belly-bursting trypsin, carboxy- peptidases Calpain Myofibrillar proteins Softening Collagenases Connective tissue Softening and gaping of tissue TrimethylamineOxide TMAO Formaldehyde (TMAO) demethylase Source: [13,14].
Cord plasma vasopressin, erythropoietin and hypoxanthine as indices of asphyxia at birth.
In 2000, it was shown that 5-methyltetrahydrofolate (5-MTHF), the main circulating folate in the body, directly scavenged superoxide generated by the xanthine/ hypoxanthine system.
The mode of action of barley feeding may be attributed to hypoxanthine available in barley grains which is reported to have demulcent, bitter tonic and astringent activity.
Other maturation-preventing factors in follicular fluid are oocyte maturation inhibitor (57) and hypoxanthine, (58) which acts only in combination with cAMP.
Xanthine Oxidoreductase (XOR) is a rate-limiting enzyme of the purine degradation pathway, oxidizing hypoxanthine into xanthine and xanthine into uric acid.
However, in the case of uric acid, xanthine and hypoxanthine and the high activity of the enzyme xanthine oxidase, which converts hypoxanthine and xanthine into uric acid, the excretion of allantoin and uric acid is approximately 98% of urinary purine derivatives.
5) Human genes: TBP, TATA box binding protein; UBC, ubiquitin C; SDHA, succinate dehydrogenase complex, subunit A, flavoprotein (Fp); RLP13, receptor like protein 13; YHWAZ, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; HMBS, hydroxymethylbilane synthase; B2M, fi-2 microglobin; hypoxanthine phosphoribosyltransferase 1; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; RPS18, ribosomal protein S18; ACTB, actin, beta; GSS, glutathione synthetase (hGus); 36B4, acidic ribosomal phosphoprotein P0.