ichthyosis vulgaris


Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to ichthyosis vulgaris: atopic dermatitis

ichthyosis vul·ga·ris

 (vŭl-gā′rəs, -gâr′əs)
n.
A genetic skin disorder characterized by dry, thickened, scaly skin, especially on the limbs, and prominent lines on the palms and soles, with symptoms usually developing in childhood.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
Ichthyosis vulgaris is the most common of these conditions and often presents in early childhood during the first year of life.
Ichthyosis is derived from the Greek word for fish, "ichthys." Ichthyosis vulgaris, the most common, often presents in early childhood during the first year of life.
Owing to atopic dermatitis, diaper dermatitis, urticaria and dyshidrotic eczema, xerosis, and ichthyosis vulgaris, 5 (19.2%) cases were referred to the dermatology polyclinic.
Vesicular lesions confined to hands and feet have been reported in two adults in a study from South India.4 Exacerbation of existing dermatoses has been described in CKG.4,11 Exacerbation of psoriasis, ichthyosis vulgaris, melasma and darkening of melanocytic nevi was observed in this study.
Several studies have shown that the c.3321delA mutation was associated with various AD-associated phenotypes, most of which are related to dry skin phenotypes, including xerosis, ichthyosis vulgaris (IV), and palmar hyperlinearity.[sup][2] In this study, we used high-resolution melting analysis (HRMA) with unlabeled probe for the detection of c.3321delA mutation in Chinese AD patients and investigated the genotype-phenotype correlation between c.3321delA and atopic characteristics.
About 1 in 10 individuals of European ancestry carry one FLG null mutation, meaning that such individuals have only about half of the normal FLG protein in their skin, resulting in dry skin and/or ichthyosis vulgaris and a high risk for AD.
A study of 100 ama X-hosa children in South Africa with severe AD and ichthyosis vulgaris symptoms revealed no FLG mutations.
Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function.