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Lack of prosperity, happiness, or health.
a state of lacking health, solvency, or contentment.
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|Noun||1.||ill-being - lack of prosperity or happiness or health|
miserableness, misery, wretchedness - a state of ill-being due to affliction or misfortune; "the misery and wretchedness of those slums is intolerable"
adversity, hard knocks, hardship - a state of misfortune or affliction; "debt-ridden farmers struggling with adversity"; "a life of hardship"