Besides, there has been challenge for the development of synthetic methods for 1-tetrasubstituted-2, 2, 2-trifluoroethylamines which becomes difficult to access by hydrogenation of reductive amination and
imines of ketones.
Rao, Synthesis and Mesomorphism of New Chiral
Imines and Copper(II) Complexes, J.
The classical synthesis of these compounds involves cycloaddition of monochloroacetyl chloride with
imines (Schiff base) resulting in formation of 2-azetidinone [12].
Comments on Ab initio studies on the mechanism of the cycloaddition reaction of fluoroketene with
imines: Substituent effects.
The synthetic strategy for the synthesis of
imines 8a-g has been described in the Scheme 3, involves reaction of acid hydrazide 1 with thiosemicarbazide to give first on a product it is 1-((5-amino-1,3,4-thiadiazol-2-yl)methyl)-3H-benzo[f]chromen-3-one 7, which is considered as starting material for the synthesis of
imines 8a-f and 8g by its reaction with substituted aldehydes or isatin as shown in Scheme 3.
The formation of
imines as by-products of the benzoxazine polymerization process has been hypothesized by several authors [31, 32].
To a lesser extent, the compounds with negative photochromism [10]--norbornadienes [11, 12], acylotropic enaminoketones [13], and azomethine
imines [14]--are described.
The reaction of acetaldehyde with most amino acids generates relatively free and stable
imines [10].
For diclofenac, several possible reactive intermediates have been postulated, including the 2,5- and 2,4'-quinone
imines and both the parent and 4'-hydroxy-diclofenac acyl-glucuronides.
El-Lateef, "Experimental and computational investigation on the corrosion inhibition characteristics of mild steel by some novel synthesized
imines in hydrochloric acid solutions," Corrosion Science, vol.
SYNTHESIS OF CHIRAL
IMINES AND AMINES ON SILICA **, Jesse Wayson *, Chelsea Desbiens, McCray Malcolm, and John T.
The majority of chapters discuss the chemistry, pharmacology, molecular biology, and detection of particular classes of toxins including the newly included categories as well as PSP toxins, polytoxins, ostreocins, cyanobacterial toxins, cylindrospermopsin, cyclic
imines, and polyketides, punctuated with additional chapters regarding therapeutics, nutraceuticals, drug development from toxins, organic synthesis reactant libraries, and toxic ingestion symptoms.
