Haskova V, Kaslik J, Riha I, et al: Simple method of circulating immune complex
detection in human sera by polyethyleneglycol precipitation.
The classical presentation of CNS in the setting of HIV-1 infection with a biopsy finding consistent with HIV immune complex
disorder will strongly support HIV-1 as a secondary cause of CNS in this case, although tissue for immunofluorescence was suboptimal and lights microscopy did not show microcytic tubular dilatation (a typical finding of nephropathy in the setting of HIV).
In the case of immune mediated hemorrhage in the lung, the hypotheses for vessel leak are (1) vessel injury from neutrophil activation (e.g., through antineutrophil antibodies (ANCA associated vasculitis, AAV)), (2) immune complex
deposition with activation of complement, anaphylatoxin, and mast cells, or (3) abnormal lymphocyte inflammation and injury [14-16].
 reported the development of nephrotic range proteinuria in 8 SLE patients with no evidence of peripheral capillary immune complex
deposition and called it glomerular podocytopathy.
Three different forms of renal AEs have been reported so far: acute tubulointerstitial nephritis (ATIN), immune complex
GN, and minimal change disease [4-7].
Although immune complex
disease can be systemic, involving many organs, in the context of this review, we deal with localized deposition of immune complexes
in cutaneous and mucosal vasculature.
On day 35 significantly (P<0.05) higher ELISA antibody titer was observed in group A vaccinated with immune complex
We have previously reported that the prevalence of sulphonamide antibodies observed in this study group was 22% by both methods-drug-absorption and immune complex
crescentic GN with granular staining of glomeruli for immunoglobulins or complement, and 3.
One of the main areas of revision included the description of 2 pathophysiologically different groups of small vessel vasculitis including immune complex
vasculitis and AAV (Table 1).
deposition is also considered a mechanism leading to activation of the complement cascade.
Wu et al., "Immune complex
formation in human diabetic retina enhances toxicity of oxidized LDL towards retinal capillary pericytes," Journal of Lipid Research, vol.