immunoglobulin M


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Related to immunoglobulin M: immunoglobulin D, immunoglobulin G, immunoglobulin A

immunoglobulin M

n. Abbr. IgM
1. The class of antibodies that are the first to appear after initial exposure to an antigen and that function to activate the complement system, promote phagocytosis of pathogens, and neutralize toxins. IgM antibodies are composed of five identical subunits and are found chiefly in the blood.
2. An antibody of this class.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.immunoglobulin M - one of the five major classes of immunoglobulins; involved in fighting blood infections and in triggering production of immunoglobulin G
Ig, immune gamma globulin, immune globulin, immune serum globulin, immunoglobulin - a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response
References in periodicals archive ?
It causes overproduction of monoclonal immunoglobulin M (IgM) antibody resulting in thickening of the blood, which can lead to many complications.
Persistence of virus-reactive serum immunoglobulin M antibody in confirmed West Nile virus encephalitis cases.
Extensive cultures and serologic studies for microbial and viral infections were all negative, whereas tests for immunoglobulin G and immunoglobulin M antibodies against the mumps virus were both positive.
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