TARA-002 is an investigational cellular therapy based on OK-432, an immunostimulant
, currently approved in Japan and Taiwan, that has been the standard of care for LMs for over 20 years.
Once issued, the allowed claims of the '839 application will provide IP coverage for the ALT-702 development program, a targeted tumor immunostimulant
designed to act locally to reverse local immunosuppression within the tumor microenvironment and stimulate antitumor immune responses.
(18) 50 mg/kg/day propolis showed an immunostimulant
effect and did not cause any side-effects in rabbits.
However, it is important to mention that plants, in addition to antimicrobial and immunostimulant
molecules, contain molecules such as phytic acid and tannins that can affect cultured organisms (Bairagi et al., 2002; El-Adawy, 2002; Flores-Miranda et al., 2014); thus, the amount and frequency of application in the feed must be determined.
Nagarathna et al (2014) who have reported the immunostimulant
properties of Kigelia africana.
(19) detected the immunostimulant
antigens in soluble exogenous antigens in Leishmania donovani and used the microscopic method to check the viability of promastigotes.
 Different type of extracts from different part of plants was used for different activities, for example, aqueous extract - immunostimulant
activity,  the ethanolic extract of the flowers  and methanolic leaf extracts - antipyretic activity,  chloroform extract of stem bark anti-inflammatory activity.
Attempts also have been made to improve body immunity and local uterine defence mechanism to fight against uterine infection by using different immunostimulant
and immunomodulators as recent technique in improving fertility at field level.
Aqueous extract from different medicinal plants as anticoccidial, growth promotive and immunostimulant
Immunostimulating agents: An immunostimulant
is a naturally occurring compound that modulates the immune system by increasing the host's resistance against diseases that in most circumstances are caused by pathogens .
Antiviral and immunostimulant
therapies were administered, resulting in an improved general condition.
The drug classes included nucleosides analogues including adenosine analogues (Adefovir and Tenofovir), guanosine analogues (Entecavir and Ribavirin), cytidine analogue (Lamivudine), immunostimulant
(Cycloferon), and Interferon-like analogues (Interferon, Pegylated Interferon alpha-2a).