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n.1.The state of being without perforation.
References in periodicals archive ?
Renal agenesis and anal imperforation are inconstant characteristics.
He postulated that a small localized lesion would lead to anal imperforation and mild vertebral anomalies, larger lesions would lead to urinary tract and gastrointestinal malformations and lastly, extreme lesions would cause lower limb fusion and anomalies associated with Sirenomelia.
These processes contribute to disruption of fetal neural tube imperforation in the early stages of embryogenesis and development of NTDs (Botto and Yang, 2000).