Arimoclomol is in clinical development at Orphazyme for the treatment of Niemann-Pick disease Type C, Gaucher disease, sporadic Inclusion Body
Myositis, and amyotrophic lateral sclerosis.
Orphazyme A/S (CPH:ORPHA.CO), a biopharmaceutical company dedicated to developing treatments for patients living with rare diseases, announced on Tuesday full enrolment of its phase II/III trial of arimoclomol for the treatment of sporadic Inclusion Body
Key words: Falconid HV-1, herpesvirus, inclusion body
, hepatitis, splenitis, captive, avian, falcons, owls, pigeons
Strategies for the recovery of active proteins through refolding of bacterial inclusion body
119th ENMC international workshop: Trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body
myositis, 10-12 October 2003, Naarden, the Netherlands.
This study reveals the presence of two distinct groups of FAdV-4 and FAdV-11 in chickens affected with hydropericardium syndrome and inclusion body
coli) BL21 (DE3) inclusion body
and refolded it using a buffer lacking a proper redox conditions.
myositis (IBM) is the most common acquired myopathy in patients over 50 years .
myositis is a rare acquired idiopathic inflammatory myopathy with the insidious onset of asymmetric and distal muscle weakness that characteristically involves the quadriceps, tibialis anterior, and forearm flexors.
Intracellular infection becomes initiated with infectious but metabolically inert elementary body (EB) which differentiates within the cell inside of membrane-associated vacuole (referred to as an inclusion body
) into metabolically active but noninfective reticulate (RB) body .
As can be seen from Figure 2, simultaneous addition of RSV and the pathogen is accompanied by a dramatic inhibition of inclusion body
formation in McCoy cells.
Global Markets Direct's, 'Inclusion Body
Myositis (IBM) - Pipeline Review, H1 2016', provides an overview of the Inclusion Body
Myositis (IBM) pipeline landscape.