hapten

(redirected from incomplete antigen)
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Related to incomplete antigen: bivalent antibody, antigenic load

hap·ten

 (hăp′tĕn′) also hap·tene (-tēn′)
n.
A small molecule that reacts with a specific antibody but does not induce an immune response unless bound to a larger molecule, usually a protein.

[German : Greek haptein, to fasten + German -en, noun suffix (from Greek -ēnē, -ene).]

hap·ten′ic adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

hapten

(ˈhæptən) or

haptene

n
(Physiology) immunol an incomplete antigen that can stimulate antibody production only when it is chemically combined with a particular protein
[C20: from German, from Greek haptein to fasten]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

hap•ten

(ˈhæp tɛn)

also hap•tene

(-tin)

n.
a substance that reacts with antibodies but cannot by itself stimulate more antibodies; a partial antigen.
[1920–25; < German < Greek hápt(ein) to grasp + German -en -ene]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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References in periodicals archive ?
SS is an incomplete antigen because of its small molecular mass that caused its poor immunogenicity (Han et al., 2016).
Factors that I think are most important relating to DTaP vaccine failure are as follows: decay in antibody over time; a T helper (Th) 1 /Th2 versus a Th1, Th17 cellular response; incomplete antigen package; incorrect balance of antigens in the vaccine; linked-epitope sup pression; and the occurrence of pertactin-deficient B.