index case


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Related to index case: index patient, primary case

index case

n.
1. The earliest identified occurrence of a disease or disorder, usually as part of an epidemiological investigation of a patient population or a genetic study of a family.
2. The first patient who has such a disease or disorder. Also called proband, propositus.

index case

n
(Medicine) med the first case of a disease, or the primary case referred to in a report
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.index case - the earliest documented case of a disease that is included in an epidemiological study
epidemiology - the branch of medical science dealing with the transmission and control of disease
patient - a person who requires medical care; "the number of emergency patients has grown rapidly"
References in periodicals archive ?
'The index case was a seven-year-old child who took ill on July 2, 2019, with similar symptoms of fever and yellowness of the eyes but was referred to the General Hospital, Iboko.
Three of the five females were probably secondary ones exposed to the index case who reported a history of direct contact with camels.
We defined the index case as the first chikungunya patient reported by the NDSS within this region.
The index case was brought to emergency with bilateral painful lower limbs.
On the one side, the authors described that the patient experienced 'recurrent episodes of loss of consciousness (in the absence of seizures).' In the next sentence, they state that 'the duration of these episodes was about 1 min while the seizure frequency was around 5-6 times per year.' These statements are contradictory and it remains unclear when the first seizures truly occurred in the index case. What do the authors mean with 'in the absence of seizures?' According to the case description, it is conceivable that the onset of seizures was at the age 8 years, but this issue requires further specification.
Vytiaco explained that the government was not able to establish the index case, or the very first farm affected by AI, due to non-reporting by farmers.
The researchers investigated the cluster, which comprised the family of the index case (mother, father, three siblings).
Eligible child contacts were aged below 5 years old and shared the same household with a selected index case within 3 months prior to the diagnosis of the latter.
(7) Unrecognized seropositive individuals may include family members of the index case, who share the same source of brucellosis and similar genetic and environmental risk factors for the disease.
Here, we present a family in which MEN2A was detected in the index case and two brothers had detected pheochromocytoma and medullary thyroid cancer.
An association of these younger patients with rickets, Down's syndrome, or a familial type of myelofibrosis has often been reported.1 The index case is interesting as it was found in a 6-year old and there was no underlying cause.