index case

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Related to index cases: index patient, primary case

index case

n.
1. The earliest identified occurrence of a disease or disorder, usually as part of an epidemiological investigation of a patient population or a genetic study of a family.
2. The first patient who has such a disease or disorder. Also called proband, propositus.

index case

n
(Medicine) med the first case of a disease, or the primary case referred to in a report
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.index case - the earliest documented case of a disease that is included in an epidemiological study
epidemiology - the branch of medical science dealing with the transmission and control of disease
patient - a person who requires medical care; "the number of emergency patients has grown rapidly"
References in periodicals archive ?
The index cases were in contact with or resided on a farm where camels were kept.
We excluded 6 households with multiple index cases, 5 households with influenza virus infections of mixed subtypes, and 24 households with index cases that were initially positive for influenza by rapid antigen test but not confirmed positive by RT-PCR.
Children exposed to index cases with TB, particularly sputum smear-positive pulmonary TB (PTB), are at risk of infection and when infected, infants and young children (<5 years old) are at high risk of developing the disease [2,3].
In this study, we screened pediatric and adult family members of index cases with brucellosis to detect unrecognized infected family members.
Following the investigation of index cases and their families, we identified 21 patients (16 children, 5 adults) diagnosed with hypophosphatemic rickets from 13 families.
Subjects and Methods: A total of 125 children suffering from active tuberculosis (index cases)aged 12 years or less were randomly selected from the outpatient department of a tertiary care hospital of Hyderabad.
The index cases were neither HIV positive nor where on any immunosuppressant medication but developed splenic lesions, reflecting some other hitherto unknown predisposing factor for such lesions.
THE LARGEST MEASLES OUTBREAK in the United States in more than 2 decades, with an attack rate several orders of magnitude larger than the usual annual nationwide incidence of the disease, could have been better controlled if clinicians had recognized the index cases sooner, according to a report published in the New England Journal of Medicine.
Two index cases developed in young Amish men (aged 22 and 23 years) who had just returned from a church-sponsored trip to the Philippines to perform charitable work among victims of a typhoon.
To measure improvements in response indicators and outcomes over time, data from investigations of 12 of 15 outbreaks in remote areas with illness onset dates of index cases during July 16-November 20, 2014, were analyzed.